Hysteroscopic Transcervical Resection for Atypical Polypoid Adenomyoma of the Uterus: A Valid, Fertility-Preserving Option

Tatsuyuki Chiyoda, Bao Liang Lin, Keiko Saotome, Shunki Kiyokawa, Sakura Nakada

研究成果: Article査読

9 被引用数 (Scopus)

抄録

Study Objective To evaluate hysteroscopic transcervical resection (TCR) for atypical polypoid adenomyoma of the uterus (APA). Design Retrospective study (Canadian Task Force classification II-2). Setting Single tertiary hospital. Patients Women who underwent TCR for APA at Kawasaki Municipal Hospital between 2003 and 2015. Interventions Clinical records were obtained. Measurements and Main Results Thirty-five patients with APA were evaluated. The median patient age was 35 years (range, 23–43 years), and the median tumor diameter was 22 mm (range, 9–51 mm). The median duration of observation after the first TCR was 34.0 months (range, 4.2–133.7 months). In 19 patients, the tumor recurred after the first TCR. A second TCR was performed in 13 patients, 11 of whom experienced recurrence. A third TCR was performed in 7 patients, all 7 of whom experienced recurrence. A fourth TCR was performed in 4 patients, 3 of whom experienced recurrence. The recurrence rate after the second TCR was higher than that after the first TCR (71.4%–84.6% vs 54.3%; p <.01, t test). The median disease-free interval was 12.4 months after the first TCR, 15.3 months after the second TCR, 10.5 months after the third TCR, and 10.9 months after the fourth TCR. Seven patients progressed to endometrial cancer; however, there was no mortality. Six of the 35 patients conceived, and 4 had a normal spontaneous delivery. Conclusion Owing to disease-free intervals that follow treatment, TCR is a promising treatment modality as a fertility-preserving option for patients with APA under careful observation. Twenty percent of patients with APA develop cancer; however, the present study showed no mortality.

本文言語English
ページ(範囲)163-169.e1
ジャーナルJournal of Minimally Invasive Gynecology
25
1
DOI
出版ステータスPublished - 2018 1

ASJC Scopus subject areas

  • 産婦人科学

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