Identification and characterization of mouse type II platelet-derived growth factor receptor α transcript

Yusuke Minato, Yoshiaki Nihei, Yuki Kodama, Etsu Tashiro, Mai Kanai, Masaya Imoto

研究成果: Article査読

1 被引用数 (Scopus)

抄録

Recently, we identified a novel human platelet-derived growth factor (PDGF) receptor α mRNA (type II) that differs from the known human PDGF receptor α mRNA (type I) only in its 5′-untranslated region and is regulated by E2F-1. In this study, we determined the nucleotide sequence of the mouse type II PDGF receptor α mRNA and found that the expression of this transcript was regulated by E2F-1 through an E2F-1-responsive sequence located +711/+718 downstream of the transcription start site of the type I transcript. Furthermore, we observed embryo-predominant expression of the type II transcript.

本文言語English
ページ(範囲)759-766
ページ数8
ジャーナルBioscience, Biotechnology and Biochemistry
72
3
DOI
出版ステータスPublished - 2008
外部発表はい

ASJC Scopus subject areas

  • バイオテクノロジー
  • 分析化学
  • 生化学
  • 応用微生物学とバイオテクノロジー
  • 分子生物学
  • 有機化学

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