Identification of 27-Nor-3a, 7α, 12α-Trihydroxycoprostan-24-One Apparently Derived from 3α, 7α, 12α-Trihydroxy-24-Oxocoprostanoic Acid, A Postulated Intermediate of Bile Acid Biosynthesis

Masatoshi Yuri, Marie Tokumoto, Noriyuki Hara, Yoshinori Fujimoto, Noriko Kobayashi, Masuo Morisaki

研究成果: Article

12 引用 (Scopus)

抜粋

Incubation of [27-13C]-3a,7a,12a-trihydroxycoprost-24-en-26-oic acid with rat liver homogenate followed by l3C-NMR analysis of the incubation product has resulted in the identification of [26-13C]-27-nor-3a,7a,12a-trihydroxycoprostan-24-one, supporting the idea that the substrate has been metabolized into 3a,7a,12a-trihydroxy-24-oxocoprostan-26-oic acid CoA derivative.

元の言語English
ページ(範囲)1327-1329
ページ数3
ジャーナルChemical and Pharmaceutical Bulletin
41
発行部数7
DOI
出版物ステータスPublished - 1993 1 1

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery

フィンガープリント Identification of 27-Nor-3a, 7α, 12α-Trihydroxycoprostan-24-One Apparently Derived from 3α, 7α, 12α-Trihydroxy-24-Oxocoprostanoic Acid, A Postulated Intermediate of Bile Acid Biosynthesis' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

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