抄録
Glycoconjugate-binding molecules can contribute a great deal to carbohydrate research and carbohydrate-related diseases. However, it is difficult to obtain carbohydrate-specific antibodies due to low immunogenicity of glycoconjugates. Recent phage-display technology serves a new methodology to identify glycoconjugate-specific molecules effectively from large repertory of candidates. Many libraries such as peptide library, antibody library, and mutation lectin library have been applied for this purpose. By using this system, we will be able to design carbohydrate-binding molecules having the affinity and specificity we need.
本文言語 | English |
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ページ(範囲) | 133-145 |
ページ数 | 13 |
ジャーナル | Trends in Glycoscience and Glycotechnology |
巻 | 19 |
号 | 107 |
DOI | |
出版ステータス | Published - 2007 5月 |
ASJC Scopus subject areas
- 生化学
- 有機化学