Identification of oligosaccharide-recognition molecules by phage-display technology

研究成果: Short survey査読

1 被引用数 (Scopus)

抄録

Glycoconjugate-binding molecules can contribute a great deal to carbohydrate research and carbohydrate-related diseases. However, it is difficult to obtain carbohydrate-specific antibodies due to low immunogenicity of glycoconjugates. Recent phage-display technology serves a new methodology to identify glycoconjugate-specific molecules effectively from large repertory of candidates. Many libraries such as peptide library, antibody library, and mutation lectin library have been applied for this purpose. By using this system, we will be able to design carbohydrate-binding molecules having the affinity and specificity we need.

本文言語English
ページ(範囲)133-145
ページ数13
ジャーナルTrends in Glycoscience and Glycotechnology
19
107
DOI
出版ステータスPublished - 2007 5

ASJC Scopus subject areas

  • 生化学
  • 有機化学

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