Immobilization of Natural Products on Glass Slides by Using a Photoaffinity Reaction and the Detection of Protein-Small-Molecule Interactions

Naoki Kanoh, Saori Kumashiro, Siro Simizu, Yasumitsu Kondoh, Satoru Hatakeyama, Hideo Tashiro, Hiroyuki Osada

研究成果: Article

128 引用 (Scopus)

抜粋

Library on a glass slide: A variety of small molecules, including complex natural products, are introduced to glass slides using a photoaffinity reaction (see picture). The small molecules retain the inherent ability to interact with the relevant binding proteins. Importantly, this immobilization procedure does not require a specific functional group, and can be applied for use with a diverse small-molecule library.

元の言語English
ページ(範囲)5584-5587
ページ数4
ジャーナルAngewandte Chemie - International Edition
42
発行部数45
DOI
出版物ステータスPublished - 2003 11 24
外部発表Yes

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ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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