@article{b1017a6f061b4457b7c976aa778c980b,
title = "Immune checkpoint inhibitors in the onset of myasthenia gravis with hyperCKemia",
abstract = "Immune checkpoint inhibitors sometimes cause neuromuscular adverse events. Although a few cases of myasthenia gravis with hyperCKemia triggered by immune checkpoint inhibitors have been described, conclusive evidence remains limited. We conducted a systematic review of published cases of myasthenia gravis with hyperCKemia related to immune checkpoint inhibitors. Moreover, we tested anti-striational antibodies in the case of myasthenia gravis with myositis after nivolumab administration. We located 17 published case reports. Anti-striational antibodies were tested in six cases and five cases were positive. Our systematic analyses revealed poor prognosis in myasthenia gravis combined hyperCKemia with immune checkpoint inhibitors.",
author = "Koutaro Takamatsu and Shunya Nakane and Shigeaki Suzuki and Takayuki Kosaka and Satoshi Fukushima and Toshihiro Kimura and Azusa Miyashita and Akihiro Mukaino and Shiori Yamakawa and Keisuke Watanabe and Masatoshi Jinnin and Yoshihiro Komohara and Hironobu Ihn and Yukio Ando",
note = "Funding Information: This study was supported by Japan Society for the Promotion of Science KAKENHI Grant Numbers JP17K09781, JP16K09695. We thank H. Matsuo, O. Higuchi, and Y. Maeda for helpful discussions and for measuring the anti-LRP4 and ganglionic AChR autoantibodies. Publisher Copyright: {\textcopyright} 2018 The Authors. Annals of Clinical and Translational Neurology published by Wiley Periodicals, Inc on behalf of American Neurological Association.",
year = "2018",
month = nov,
doi = "10.1002/acn3.654",
language = "English",
volume = "5",
pages = "1421--1427",
journal = "Annals of Clinical and Translational Neurology",
issn = "2328-9503",
publisher = "John Wiley and Sons Ltd",
number = "11",
}