Immune responses to gut microbiota-commensals and pathogens

Takeshi Tanoue, Yoshinori Umesaki, Kenya Honda

研究成果: Review article査読

43 被引用数 (Scopus)

抄録

The mammalian alimentary tract harbors hundreds of species of commensal microorganisms that intimately interact with the host immune system. Within the gut, the immune system actively reacts with potentially pathogenic microbes, while simultaneously remaining ignorant towards the vast majority of non-pathogenic microbiota. The disruption of this delicate balance results in inflammatory bowel diseases. In this review, we describe the recent advances in our understanding of how host-microbiota interactions shape the immune system and how they affect the responses against pathogenic bacteria.

本文言語English
ページ(範囲)224-233
ページ数10
ジャーナルGut microbes
1
4
DOI
出版ステータスPublished - 2010
外部発表はい

ASJC Scopus subject areas

  • 微生物学
  • 消化器病学
  • 微生物学(医療)
  • 感染症

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