Immunohistochemical study is helpful for the diagnosis of cerebellar clear cell ependymoma with atypical radiological findings: Case report

Takuro Hayashi, Hiromichi Miyazaki, Naomi Ishiyama, Kaori Kameyama

研究成果: Article

3 引用 (Scopus)

抄録

A 67-year-old male presented with a clear cell ependymoma with symptoms of ataxic gait and dizziness. Magnetic resonance imaging showed a ring enhanced and circumscribed mass lesion with some cysts in the left cerebellar hemisphere, and the vertebral artery angiogram showed the vascurality of the tumor fed by both the left posterior inferior cerebellar artery and the left superior cerebellar artery mainly. They demonstrated suspicious finding of metastatic tumor, glioblastoma, or cystic meningioma. Surgery via the left suboccipital approach revealed a whitish and solid tumor, which was demarcated from the cerebellar parenchyma and had no continuity with the 4th ventricle. Total resection of the tumor was successfully performed. The hematoxilyn-eosin staining of the surgical specimen was similar to hemangioblastoma or oligodendroglioma, however, immunohistochemical findings for glial fibrillary acidic protein, vimentin, epithelial membrane antigen, and factor VI were compatible with clear cell ependymoma. The patient's postoperative course was uneventful, and his symptoms improved. Clear cell ependymoma is known as a variant of ependymoma, which is usually located at the foramen of Monro. We think that the immunohistochemical study is highly helpful for the diagnosis of the cerebellar tumor with atypical presentation such as our case.

元の言語English
ページ(範囲)1113-1117
ページ数5
ジャーナルNeurological Surgery
33
発行部数11
出版物ステータスPublished - 2005 11

Fingerprint

Ependymoma
Neoplasms
Arteries
Cerebellar Neoplasms
Hemangioblastoma
Oligodendroglioma
Fourth Ventricle
Cerebral Ventricles
Mucin-1
Vertebral Artery
Glial Fibrillary Acidic Protein
Dizziness
Meningioma
Vimentin
Glioblastoma
Eosine Yellowish-(YS)
Gait
Cysts
Angiography
Magnetic Resonance Imaging

ASJC Scopus subject areas

  • Clinical Neurology

これを引用

Immunohistochemical study is helpful for the diagnosis of cerebellar clear cell ependymoma with atypical radiological findings : Case report. / Hayashi, Takuro; Miyazaki, Hiromichi; Ishiyama, Naomi; Kameyama, Kaori.

:: Neurological Surgery, 巻 33, 番号 11, 11.2005, p. 1113-1117.

研究成果: Article

@article{8bdbb6ece33b4418b3070f46d321bdf1,
title = "Immunohistochemical study is helpful for the diagnosis of cerebellar clear cell ependymoma with atypical radiological findings: Case report",
abstract = "A 67-year-old male presented with a clear cell ependymoma with symptoms of ataxic gait and dizziness. Magnetic resonance imaging showed a ring enhanced and circumscribed mass lesion with some cysts in the left cerebellar hemisphere, and the vertebral artery angiogram showed the vascurality of the tumor fed by both the left posterior inferior cerebellar artery and the left superior cerebellar artery mainly. They demonstrated suspicious finding of metastatic tumor, glioblastoma, or cystic meningioma. Surgery via the left suboccipital approach revealed a whitish and solid tumor, which was demarcated from the cerebellar parenchyma and had no continuity with the 4th ventricle. Total resection of the tumor was successfully performed. The hematoxilyn-eosin staining of the surgical specimen was similar to hemangioblastoma or oligodendroglioma, however, immunohistochemical findings for glial fibrillary acidic protein, vimentin, epithelial membrane antigen, and factor VI were compatible with clear cell ependymoma. The patient's postoperative course was uneventful, and his symptoms improved. Clear cell ependymoma is known as a variant of ependymoma, which is usually located at the foramen of Monro. We think that the immunohistochemical study is highly helpful for the diagnosis of the cerebellar tumor with atypical presentation such as our case.",
keywords = "Cerebellum, Clear cell ependymoma, Cyst, MRI, Ring enhance",
author = "Takuro Hayashi and Hiromichi Miyazaki and Naomi Ishiyama and Kaori Kameyama",
year = "2005",
month = "11",
language = "English",
volume = "33",
pages = "1113--1117",
journal = "Neurological Surgery",
issn = "0301-2603",
publisher = "Igaku-Shoin Ltd",
number = "11",

}

TY - JOUR

T1 - Immunohistochemical study is helpful for the diagnosis of cerebellar clear cell ependymoma with atypical radiological findings

T2 - Case report

AU - Hayashi, Takuro

AU - Miyazaki, Hiromichi

AU - Ishiyama, Naomi

AU - Kameyama, Kaori

PY - 2005/11

Y1 - 2005/11

N2 - A 67-year-old male presented with a clear cell ependymoma with symptoms of ataxic gait and dizziness. Magnetic resonance imaging showed a ring enhanced and circumscribed mass lesion with some cysts in the left cerebellar hemisphere, and the vertebral artery angiogram showed the vascurality of the tumor fed by both the left posterior inferior cerebellar artery and the left superior cerebellar artery mainly. They demonstrated suspicious finding of metastatic tumor, glioblastoma, or cystic meningioma. Surgery via the left suboccipital approach revealed a whitish and solid tumor, which was demarcated from the cerebellar parenchyma and had no continuity with the 4th ventricle. Total resection of the tumor was successfully performed. The hematoxilyn-eosin staining of the surgical specimen was similar to hemangioblastoma or oligodendroglioma, however, immunohistochemical findings for glial fibrillary acidic protein, vimentin, epithelial membrane antigen, and factor VI were compatible with clear cell ependymoma. The patient's postoperative course was uneventful, and his symptoms improved. Clear cell ependymoma is known as a variant of ependymoma, which is usually located at the foramen of Monro. We think that the immunohistochemical study is highly helpful for the diagnosis of the cerebellar tumor with atypical presentation such as our case.

AB - A 67-year-old male presented with a clear cell ependymoma with symptoms of ataxic gait and dizziness. Magnetic resonance imaging showed a ring enhanced and circumscribed mass lesion with some cysts in the left cerebellar hemisphere, and the vertebral artery angiogram showed the vascurality of the tumor fed by both the left posterior inferior cerebellar artery and the left superior cerebellar artery mainly. They demonstrated suspicious finding of metastatic tumor, glioblastoma, or cystic meningioma. Surgery via the left suboccipital approach revealed a whitish and solid tumor, which was demarcated from the cerebellar parenchyma and had no continuity with the 4th ventricle. Total resection of the tumor was successfully performed. The hematoxilyn-eosin staining of the surgical specimen was similar to hemangioblastoma or oligodendroglioma, however, immunohistochemical findings for glial fibrillary acidic protein, vimentin, epithelial membrane antigen, and factor VI were compatible with clear cell ependymoma. The patient's postoperative course was uneventful, and his symptoms improved. Clear cell ependymoma is known as a variant of ependymoma, which is usually located at the foramen of Monro. We think that the immunohistochemical study is highly helpful for the diagnosis of the cerebellar tumor with atypical presentation such as our case.

KW - Cerebellum

KW - Clear cell ependymoma

KW - Cyst

KW - MRI

KW - Ring enhance

UR - http://www.scopus.com/inward/record.url?scp=27744602015&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=27744602015&partnerID=8YFLogxK

M3 - Article

C2 - 16277226

AN - SCOPUS:27744602015

VL - 33

SP - 1113

EP - 1117

JO - Neurological Surgery

JF - Neurological Surgery

SN - 0301-2603

IS - 11

ER -