抄録
Progress in stem cell research has been associated with the discovery of the presence of cancer stem cells in a variety of malignant tumors, and because these cells are resistant to anticancer agents and radiotherapy, analysis of their properties has been rapidly pursued as an important target for the treatment of cancers, including malignant brain tumors. Brain cancer stem cells (BCSCs) have been isolated from brain tumor tissue and brain tumor cell lines by using neural stem cell culture methods. Analyzing the properties of BCSCs is extremely important to developing treatment methods that target BCSCs. Although no treatment method targeting BCSCs has yet been established, several methods have been proposed based on their cell-biological characteristics. This article describes therapeutic strategies that target drug-resistance molecules and stem-cell-associated molecules as well as immunotherapy targeted at BCSCs.
| 元の言語 | English |
|---|---|
| ページ（範囲） | 48-50 |
| ページ数 | 3 |
| ジャーナル | Open Cancer Immunology Journal |
| 巻 | 3 |
| 出版物ステータス | Published - 2010 |
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ASJC Scopus subject areas
- Cancer Research
- Immunology
- Oncology
これを引用
Immunotherapy targeted at brain cancer stem cells. / Toda, Masahiro.
：: Open Cancer Immunology Journal, 巻 3, 2010, p. 48-50.研究成果: Article
}
TY - JOUR
T1 - Immunotherapy targeted at brain cancer stem cells
AU - Toda, Masahiro
PY - 2010
Y1 - 2010
N2 - Progress in stem cell research has been associated with the discovery of the presence of cancer stem cells in a variety of malignant tumors, and because these cells are resistant to anticancer agents and radiotherapy, analysis of their properties has been rapidly pursued as an important target for the treatment of cancers, including malignant brain tumors. Brain cancer stem cells (BCSCs) have been isolated from brain tumor tissue and brain tumor cell lines by using neural stem cell culture methods. Analyzing the properties of BCSCs is extremely important to developing treatment methods that target BCSCs. Although no treatment method targeting BCSCs has yet been established, several methods have been proposed based on their cell-biological characteristics. This article describes therapeutic strategies that target drug-resistance molecules and stem-cell-associated molecules as well as immunotherapy targeted at BCSCs.
AB - Progress in stem cell research has been associated with the discovery of the presence of cancer stem cells in a variety of malignant tumors, and because these cells are resistant to anticancer agents and radiotherapy, analysis of their properties has been rapidly pursued as an important target for the treatment of cancers, including malignant brain tumors. Brain cancer stem cells (BCSCs) have been isolated from brain tumor tissue and brain tumor cell lines by using neural stem cell culture methods. Analyzing the properties of BCSCs is extremely important to developing treatment methods that target BCSCs. Although no treatment method targeting BCSCs has yet been established, several methods have been proposed based on their cell-biological characteristics. This article describes therapeutic strategies that target drug-resistance molecules and stem-cell-associated molecules as well as immunotherapy targeted at BCSCs.
KW - Cancer stem cell
KW - Glioma
KW - Immunotherapy
KW - Vaccine
UR - http://www.scopus.com/inward/record.url?scp=80555136553&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=80555136553&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:80555136553
VL - 3
SP - 48
EP - 50
JO - Open Cancer Immunology Journal
JF - Open Cancer Immunology Journal
SN - 1876-4010
ER -