[Immunotherapy targeting cancer stem cells].

Yutaka Kawakami, Maiko Matsushita, Ryo Ueda, Nobuo Tsukamoto, Shigeki Ohta

研究成果: Review article査読

2 被引用数 (Scopus)

抄録

Cancer stem cells are relatively resistant to chemotherapy, and cause relapse of cancer. Thus, various strategies to eliminate cancer stem cells have recently been exploited. One of them is immunotherapy. To develop the immunotherapy targeting cancer stem cells, tumor antigens expressed in cancer stem cells have been identified, and their use in the immunotherapy is expected. However, cancer stem cells may have an immunosuppressive ability. Therefore, blockade of the immunosuppressive mechanisms of cancer stem cells may also be required for development of effective immunotherapies against cancer stem cells.

本文言語English
ページ(範囲)2142-2146
ページ数5
ジャーナルNihon rinsho. Japanese journal of clinical medicine
70
12
出版ステータスPublished - 2012 12

ASJC Scopus subject areas

  • 医学(全般)

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