Impact of neoadjuvant and adjuvant chemotherapy on invasive lobular carcinoma: A propensity score-matched analysis of SEER data

Rurina Watanuki, Tetsu Hayashida, Takamichi Yokoe, Yuko Kawai, Masayuki Kikuchi, Ayako Nakashoji, Aiko Nagayama, Tomoko Seki, Maiko Takahashi, Yuko Kitagawa

研究成果: Article査読

2 被引用数 (Scopus)

抄録

Invasive lobular carcinoma (ILC) has a different treatment response from invasive ductal carcinoma (IDC). We assessed whether perioperative chemotherapy was associated with improved prognosis in patients with ILC. Retrospective data of women who underwent surgery for ILC were extracted from the SEER database. Subjects were divided into non-chemotherapy and chemotherapy groups. Overall, 10 537 patients were included, and 2107 patients were stratified into each group after propensity score matching. Perioperative chemotherapy significantly improved 10-year survival rates for ILC, particularly in patients with large tumor size and lymph node metastases. Perioperative chemotherapy is effective for ILC patients with proper selection.

本文言語English
ページ(範囲)1765-1770
ページ数6
ジャーナルBreast Journal
26
9
DOI
出版ステータスPublished - 2020 9 1

ASJC Scopus subject areas

  • Internal Medicine
  • Surgery
  • Oncology

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