Implantable hydrogel microfiber encapsulating pancreatic beta-cells for diabetes treatment

S. Sugimoto, Y. J. Heo, Hiroaki Onoe, T. Okitsu, H. Kotera, S. Takeuchi

研究成果: Conference contribution

2 引用 (Scopus)

抄録

This paper describes implantable hydrogel microfibers encapsulating living pancreatic beta-cells for diabetes treatment. The structure of microfiber has a potential not only to implant but also to remove the pancreatic beta-cells encapsulated in the microfiber, indicating that our microfiber can be a cartridge-type device to regulate blood glucose. We successfully validated the potency of our microfibers by implanting them into chemically induced diabetic mice and normalizing their blood glucose. We believe that our method to encapsulate pancreatic beta-cells in the microfibers could be useful for cell-based medicine targeted to diabetes mellitus.

元の言語English
ホスト出版物のタイトル15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
ページ1248-1250
ページ数3
2
出版物ステータスPublished - 2011
外部発表Yes
イベント15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 - Seattle, WA, United States
継続期間: 2011 10 22011 10 6

Other

Other15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
United States
Seattle, WA
期間11/10/211/10/6

Fingerprint

Medical problems
Hydrogels
Glucose
Blood
Medicine

ASJC Scopus subject areas

  • Control and Systems Engineering

これを引用

Sugimoto, S., Heo, Y. J., Onoe, H., Okitsu, T., Kotera, H., & Takeuchi, S. (2011). Implantable hydrogel microfiber encapsulating pancreatic beta-cells for diabetes treatment. : 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 (巻 2, pp. 1248-1250)

Implantable hydrogel microfiber encapsulating pancreatic beta-cells for diabetes treatment. / Sugimoto, S.; Heo, Y. J.; Onoe, Hiroaki; Okitsu, T.; Kotera, H.; Takeuchi, S.

15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011. 巻 2 2011. p. 1248-1250.

研究成果: Conference contribution

Sugimoto, S, Heo, YJ, Onoe, H, Okitsu, T, Kotera, H & Takeuchi, S 2011, Implantable hydrogel microfiber encapsulating pancreatic beta-cells for diabetes treatment. : 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011. 巻. 2, pp. 1248-1250, 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011, Seattle, WA, United States, 11/10/2.
Sugimoto S, Heo YJ, Onoe H, Okitsu T, Kotera H, Takeuchi S. Implantable hydrogel microfiber encapsulating pancreatic beta-cells for diabetes treatment. : 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011. 巻 2. 2011. p. 1248-1250
Sugimoto, S. ; Heo, Y. J. ; Onoe, Hiroaki ; Okitsu, T. ; Kotera, H. ; Takeuchi, S. / Implantable hydrogel microfiber encapsulating pancreatic beta-cells for diabetes treatment. 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011. 巻 2 2011. pp. 1248-1250
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