A reconfigurable accelerator for cell simulators called "ReCSiP" is proposed. It consists of both reconfigurable hardware and software platform. For high performance simulation, numerical solution of kinetic formulas, which require a large amount of computation, are processed on the reconfigurable hardware. It also provides programming interface for developing cell simulators. In this paper, Michaelis-Menten solver is designed and implemented on ReCSiP. The result of preliminary evaluation shows that ReCSiP is 8 times faster than Intel PentiumIII 1.13GHz when simple metabolic simulations are executed.