In vivo and in vitro evaluation of the biocompatibility of the hydroxyapatite-PMMA hybrid materials having mechanical property similar to that of cortical bone

M. Aizawa, M. Ito, K. Itatani, H. Suemasu, A. Nozue, I. Okada, M. Matsumoto, M. Ishikawa, H. Matsumoto, Y. Toyama

研究成果: Conference article

9 引用 (Scopus)

抜粋

We fabricated the Hydroxyapatite(HAp)-PMMA hybrid material having mechanical properties similar to those of the cortical bone, using porous HAp ceramics with well-controlled pore sizes and bulk polymerization of MMA monomer without solvents. The histological results showed that the present hybrid material bonded directly to bone without intervening fibrous tissue between hybrid material and newly formed bone, and that a large amount of new bone was formed around the hybrid material. In addition, the results of in vitro evaluation also showed that the hybrid material in the present investigation has good biocompatibility.

元の言語English
ページ(範囲)465-468
ページ数4
ジャーナルKey Engineering Materials
218-220
出版物ステータスPublished - 2002 1 1
イベント14th International Symposium on Ceramics in Medicine-Annual Meeting of the International Society for Ceramics in Medicine BIOCERAMICS'01 (ISCM) - Palm Springs, CA, United States
継続期間: 2001 11 142001 11 17

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

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  • これを引用

    Aizawa, M., Ito, M., Itatani, K., Suemasu, H., Nozue, A., Okada, I., Matsumoto, M., Ishikawa, M., Matsumoto, H., & Toyama, Y. (2002). In vivo and in vitro evaluation of the biocompatibility of the hydroxyapatite-PMMA hybrid materials having mechanical property similar to that of cortical bone. Key Engineering Materials, 218-220, 465-468.