In vivo evaluation of corneal epithelium seeded PVA hydrogel as an artificial corneal stroma

Hisatoshi Kobayashi; Masabumi Kato; Tetsushi Taguchi; Shigeto Shimmura; Hideyuki Miyashita; Kazuo Tsubota; Junzo Tanaka

In vivo evaluation of corneal epithelium seeded PVA hydrogel as an artificial corneal stroma

Hisatoshi Kobayashi, Masabumi Kato, Tetsushi Taguchi, Shigeto Shimmura, Hideyuki Miyashita, Kazuo Tsubota, Junzo Tanaka

眼科学

研究成果: Paper › 査読

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We have reported the transparent poly(vinyl alcohol) hydrogel with type I collagen covalently immobilized had a good affinity toward rabbit corneal epithelium. In this study, we evaluated the in vivo stability of the pre-seeded corneal epithelium on the PVA-COL. Corneal epithelium was stratification on the PVA-Col in vitro culture and the epithelium pre-seeded PVA-COL was implanted in the rabbit cornea and evaluated the in vivo stability. The pre-seeded epithelium layer was peeled off within a week. Improvement of the in vivo stability was required.

本文言語	English
ページ数	1
出版ステータス	Published - 2005 12月 1
イベント	54th SPSJ Annual Meeting 2005 - Yokohama, Japan 継続期間: 2005 5月 25 → 2005 5月 27

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Other	54th SPSJ Annual Meeting 2005
国/地域	Japan
City	Yokohama
Period	05/5/25 → 05/5/27

ASJC Scopus subject areas

工学（全般）

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title = "In vivo evaluation of corneal epithelium seeded PVA hydrogel as an artificial corneal stroma",

abstract = "We have reported the transparent poly(vinyl alcohol) hydrogel with type I collagen covalently immobilized had a good affinity toward rabbit corneal epithelium. In this study, we evaluated the in vivo stability of the pre-seeded corneal epithelium on the PVA-COL. Corneal epithelium was stratification on the PVA-Col in vitro culture and the epithelium pre-seeded PVA-COL was implanted in the rabbit cornea and evaluated the in vivo stability. The pre-seeded epithelium layer was peeled off within a week. Improvement of the in vivo stability was required.",

keywords = "Artificial cornea, Epithelium, In vivo, Pre-seeded, PVA hydrogel",

author = "Hisatoshi Kobayashi and Masabumi Kato and Tetsushi Taguchi and Shigeto Shimmura and Hideyuki Miyashita and Kazuo Tsubota and Junzo Tanaka",

year = "2005",

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T1 - In vivo evaluation of corneal epithelium seeded PVA hydrogel as an artificial corneal stroma

AU - Kobayashi, Hisatoshi

AU - Kato, Masabumi

AU - Taguchi, Tetsushi

AU - Shimmura, Shigeto

AU - Miyashita, Hideyuki

AU - Tsubota, Kazuo

AU - Tanaka, Junzo

PY - 2005/12/1

Y1 - 2005/12/1

N2 - We have reported the transparent poly(vinyl alcohol) hydrogel with type I collagen covalently immobilized had a good affinity toward rabbit corneal epithelium. In this study, we evaluated the in vivo stability of the pre-seeded corneal epithelium on the PVA-COL. Corneal epithelium was stratification on the PVA-Col in vitro culture and the epithelium pre-seeded PVA-COL was implanted in the rabbit cornea and evaluated the in vivo stability. The pre-seeded epithelium layer was peeled off within a week. Improvement of the in vivo stability was required.

AB - We have reported the transparent poly(vinyl alcohol) hydrogel with type I collagen covalently immobilized had a good affinity toward rabbit corneal epithelium. In this study, we evaluated the in vivo stability of the pre-seeded corneal epithelium on the PVA-COL. Corneal epithelium was stratification on the PVA-Col in vitro culture and the epithelium pre-seeded PVA-COL was implanted in the rabbit cornea and evaluated the in vivo stability. The pre-seeded epithelium layer was peeled off within a week. Improvement of the in vivo stability was required.

KW - Artificial cornea

KW - Epithelium

KW - In vivo

KW - Pre-seeded

KW - PVA hydrogel

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M3 - Paper

AN - SCOPUS:33645646765

T2 - 54th SPSJ Annual Meeting 2005

Y2 - 25 May 2005 through 27 May 2005

ER -

In vivo evaluation of corneal epithelium seeded PVA hydrogel as an artificial corneal stroma

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Other

ASJC Scopus subject areas

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