In vivo evaluation of ocular demodicosis using laser scanning confocal microscopy

Takashi Kojima, Reiko Ishida, Enrique Adan Sato, Tetsuya Kawakita, Osama M.A. Ibrahim, Yukihiro Matsumoto, Minako Kaido, Murat Dogru, Kazuo Tsubota

研究成果: Article査読

31 被引用数 (Scopus)

抄録

PURPOSE. To investigate the applicability of in vivo laser scanning confocal microscopy in the diagnosis and follow-up of ocular demodicosis infestation in a prospective controlled study. METHODS. Fifteen right eyes of 15 patients with blepharitis associated with cylindrical dandruff (10 males, 5 females; mean age: 62.9 ± 9 years) and eight right eyes of eight age- and sex-matched control subjects underwent HRTII/RCM, evaluation of ocular symptom scores, tear function tests including vital stainings, Schirmer test, and tear clearance test, and evaluation of mite numbers in the eyelids. RESULTS. In vivo confocal microscopy effectively disclosed the mites in the terminal bulbs of the eyelashes, which were not observed after treatment. Eyelids with demodicosis infestation showed marked inflammatory infiltrates around the meibomian glands and conjunctiva, which cleared with tea tree oil treatment. CONCLUSIONS. Laser scanning confocal microscopy seems to be an efficient noninvasive tool in the diagnosis and follow-up of ocular demodicosis infestation.

本文言語English
ページ(範囲)565-569
ページ数5
ジャーナルInvestigative Ophthalmology and Visual Science
52
1
DOI
出版ステータスPublished - 2011 1

ASJC Scopus subject areas

  • 眼科学
  • 感覚系
  • 細胞および分子神経科学

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