TY - JOUR
T1 - Incidence and risk factors for postoperative delirium after major head and neck cancer surgery
AU - Bouoka, Eisuke
AU - Kamijo, Tomoyuki
AU - Matsumoto, Teruaki
AU - Takeuchi, Mari
AU - Kitani, Takashi
AU - Nagaoka, Masato
AU - Imai, Atsushi
AU - Iida, Yoshiyuki
AU - Shimada, Ayako
AU - Takebayashi, Katsushi
AU - Niihara, Masahiro
AU - Mori, Keita
AU - Onitsuka, Tetsuro
AU - Tsubosa, Yasuhiro
AU - Takeuchi, Hiroya
AU - Kitagawa, Yuko
N1 - Publisher Copyright:
© 2016 European Association for Cranio-Maxillo-Facial Surgery.
PY - 2016/7/1
Y1 - 2016/7/1
N2 - Background Postoperative delirium is a common and serious complication after extensive surgery. This study aimed to investigate the incidence and risk factors for postoperative delirium after major head and neck cancer surgery. Methods A retrospective analysis was performed for 293 patients who underwent major head and neck cancer surgery lasting >6 h at our institution between January 2012 and November 2015. All data were assessed by two psychiatrists. Univariate and multivariate analyses were performed. Results Postoperative delirium developed in 50 (17.1%) patients; most cases (84.0%) of postoperative delirium were observed between postoperative day (POD) 1 and POD 3. Multivariate analysis revealed that an age >70 years was the significant risk factor for postoperative delirium incidence after major head and neck cancer surgery; the multivariate hazard ratio was 3.935 (95% confidence interval 1.873-8.265, p < 0.001). Conclusions Most cases of postoperative delirium after major head and neck cancer surgery were observed between POD 1 and POD 3, and a multivariate analysis revealed that an age >70 years was a significant risk factor for postoperative delirium incidence. Clinicians should pay particular attention to the possibility of delirium incidence during the first 3 days after surgery for patients aged >70 years.
AB - Background Postoperative delirium is a common and serious complication after extensive surgery. This study aimed to investigate the incidence and risk factors for postoperative delirium after major head and neck cancer surgery. Methods A retrospective analysis was performed for 293 patients who underwent major head and neck cancer surgery lasting >6 h at our institution between January 2012 and November 2015. All data were assessed by two psychiatrists. Univariate and multivariate analyses were performed. Results Postoperative delirium developed in 50 (17.1%) patients; most cases (84.0%) of postoperative delirium were observed between postoperative day (POD) 1 and POD 3. Multivariate analysis revealed that an age >70 years was the significant risk factor for postoperative delirium incidence after major head and neck cancer surgery; the multivariate hazard ratio was 3.935 (95% confidence interval 1.873-8.265, p < 0.001). Conclusions Most cases of postoperative delirium after major head and neck cancer surgery were observed between POD 1 and POD 3, and a multivariate analysis revealed that an age >70 years was a significant risk factor for postoperative delirium incidence. Clinicians should pay particular attention to the possibility of delirium incidence during the first 3 days after surgery for patients aged >70 years.
KW - Head and neck cancer
KW - Older age
KW - Postoperative delirium
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UR - http://www.scopus.com/inward/citedby.url?scp=84971619628&partnerID=8YFLogxK
U2 - 10.1016/j.jcms.2016.04.032
DO - 10.1016/j.jcms.2016.04.032
M3 - Article
C2 - 27235151
AN - SCOPUS:84971619628
SN - 1010-5182
VL - 44
SP - 890
EP - 894
JO - Journal of Cranio-Maxillofacial Surgery
JF - Journal of Cranio-Maxillofacial Surgery
IS - 7
ER -
