Incomplete Androgen Insensitivity Associated with a Thermolabile Androgen Receptor

Tomonobu Hasegawa; Yukihiro Hasegawa; Taiji Aso; Shinobu Koto; Yutaka Tsuchiya

doi:10.1507/endocrj.41.31

Incomplete Androgen Insensitivity Associated with a Thermolabile Androgen Receptor

Tomonobu Hasegawa, Yukihiro Hasegawa, Taiji Aso, Shinobu Koto, Yutaka Tsuchiya

研究成果: Article

3 引用（Scopus）

抜粋

One infant and a cousin with incomplete androgen insensitivity syndrome were reported. The familial pedigree showed that the disorder was inherited in three generations in X-linked recessive fashion. An androgen binding study of cultured genital skin fibroblast from patients showed normal maximum binding capacity and a normal apparent dissociation constant. Heat stability assay showed binding decreased to less than 30% at 41 °C compared with the amount at 30°C, indicating that the androgen receptor was thermolabile.

元の言語	English
ページ（範囲）	31-35
ページ数	5
ジャーナル	Endocrine journal
巻	41
発行部数	1
DOI	https://doi.org/10.1507/endocrj.41.31
出版物ステータス	Published - 1994 1 1
外部発表	Yes

フィンガープリント

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Endocrinology

これを引用

Hasegawa, T., Hasegawa, Y., Aso, T., Koto, S., & Tsuchiya, Y. (1994). Incomplete Androgen Insensitivity Associated with a Thermolabile Androgen Receptor. Endocrine journal, 41(1), 31-35. https://doi.org/10.1507/endocrj.41.31

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文献にアクセス

10.1507/endocrj.41.31