Induction mechanism of a single gene molecule: Stochastic or deterministic?

Minoru S.H. Ko

研究成果: Article査読

97 被引用数 (Scopus)

抄録

A new field of gene expression regulation research is emerging that has previously been overlooked. This new area is concerned with distinguishing the expression of a single gene from the averaged expression of many gene copies within the cell population. This paper reviews research focused on individual genes in inducible gene expression systems. The main experimental strategy is to measure the gene expression level of a single cell containing a single reporter gene molecule. In contrast to the commonly held belief, gene induction is found to be stochastic under certain conditions. The possible mechanisms and implications are discussed.

本文言語English
ページ(範囲)341-346
ページ数6
ジャーナルBioEssays
14
5
DOI
出版ステータスPublished - 1992
外部発表はい

ASJC Scopus subject areas

  • 生化学、遺伝学、分子生物学(全般)

フィンガープリント

「Induction mechanism of a single gene molecule: Stochastic or deterministic?」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル