Induction of DnaK and GroEL heat shock proteins by fluoroquinolones in Escherichia coli

T. Mizushima, M. Matsuo, K. Sekimizu

研究成果: Article査読

8 被引用数 (Scopus)

抄録

Various fluoroquinolones (norfloxacin, enoxacin, ofloxacin, levofloxacin, and sparfloxacin) induce DnaK and GroEL heat shock proteins in Escherichia coli. The induction is transient, consistent with the kinetics of cellular DNA relaxation. The concentrations of fluoroquinolones required for the induction are similar to those required for DNA relaxation and much higher than those required for cell death.

本文言語English
ページ(範囲)193-195
ページ数3
ジャーナルAntimicrobial Agents and Chemotherapy
41
1
DOI
出版ステータスPublished - 1997

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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