TY - JOUR
T1 - Induction of DnaK and GroEL heat shock proteins by fluoroquinolones in Escherichia coli
AU - Mizushima, T.
AU - Matsuo, M.
AU - Sekimizu, K.
PY - 1997
Y1 - 1997
N2 - Various fluoroquinolones (norfloxacin, enoxacin, ofloxacin, levofloxacin, and sparfloxacin) induce DnaK and GroEL heat shock proteins in Escherichia coli. The induction is transient, consistent with the kinetics of cellular DNA relaxation. The concentrations of fluoroquinolones required for the induction are similar to those required for DNA relaxation and much higher than those required for cell death.
AB - Various fluoroquinolones (norfloxacin, enoxacin, ofloxacin, levofloxacin, and sparfloxacin) induce DnaK and GroEL heat shock proteins in Escherichia coli. The induction is transient, consistent with the kinetics of cellular DNA relaxation. The concentrations of fluoroquinolones required for the induction are similar to those required for DNA relaxation and much higher than those required for cell death.
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U2 - 10.1128/aac.41.1.193
DO - 10.1128/aac.41.1.193
M3 - Article
C2 - 8980780
AN - SCOPUS:0031038396
VL - 41
SP - 193
EP - 195
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
SN - 0066-4804
IS - 1
ER -