Inflammatory myopathies and human leukocyte antigen

Yuko Ohnuki, Shigeaki Suzuki, Takashi Shiina

研究成果: Review article査読

抄録

Idiopathic inflammatory myopathies (IIM) are a heterogeneous group of subacute, chronic or acute systemic immune-mediated diseases of the skeletal muscles. Recently, research has shown the utility of adding new classifications of myopathies, mainly based on their pathology and the presence of specific autoantibodies. In addition, developments in genetics have helped reveal the genetic background of IIM. The human leukocyte antigen genomic region has been consistently shown to be the strongest genetic risk factor for IIM. The present review summarizes the previous and current literature on human leukocyte antigen analysis of IIM, as well as future directions for research.

本文言語English
ページ(範囲)313-317
ページ数5
ジャーナルClinical and Experimental Neuroimmunology
8
4
DOI
出版ステータスPublished - 2017 11月

ASJC Scopus subject areas

  • 神経科学(その他)
  • 免疫学
  • 免疫学および微生物学(その他)
  • 臨床神経学

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