Inflammatory pseudotumor of the stomach: Report of a highly infiltrative case with electron microscopic and immunohistochemical studies

Kenichi Kojimahara, Makio Mukai, Kazuto Yamazaki, Taketo Yamada, Tatsuro Katayama, Koh Nakada, Shigeto Uematsu, Akira Umezono, Yasuhiro Hosoda

研究成果: Article

21 引用 (Scopus)

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A large, poorly demarcated, elevated lesion over the area ranging from the lower end of the esophagus to the lesser curvature of the cardiac region was examined in a 19 year old woman, and demonstrated an irregular and highly infiltrative proliferation of spindle cells over the full thickness of the gastric wall. Although the spindle cells grew mainly in the submucosa, they penetrated the muscularis propria, leaving intact muscle tissue that formed an irregular, island‐like pattern, and reached the subserosa. The cells were identified as myofibroblasts by light microscopy, immuno‐histochemistry and electron microscopy. The present case is considered to be of an inflammatory pseudotumor due to extremely infiltrative growth of myofibroblasts. This lesion differed from inflammatory fibroid polyp (similarly consisting of proliferating myofibroblasts accompanied by inflammatory cells) in terms of age at onset, tumor size, pattern of cell proliferation and main inflammatory cell component. This report also discusses the relationship between this lesion and a very recently advocated new entity, inflammatory fibrosarcoma of the mesentery and retroperito‐neum, which is a tumour closely simulating inflammatory pseudotumor.

元の言語English
ページ(範囲)65-70
ページ数6
ジャーナルPathology international
43
発行部数1-2
DOI
出版物ステータスPublished - 1993 1

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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    Kojimahara, K., Mukai, M., Yamazaki, K., Yamada, T., Katayama, T., Nakada, K., Uematsu, S., Umezono, A., & Hosoda, Y. (1993). Inflammatory pseudotumor of the stomach: Report of a highly infiltrative case with electron microscopic and immunohistochemical studies. Pathology international, 43(1-2), 65-70. https://doi.org/10.1111/j.1440-1827.1993.tb02916.x