Inhibition of DNA topoisomerase I activity by diethylstilbestrol and its analogues

Taiko Oda, Yoshihiro Sato, Masahiko Kodama, Motohisa Kaneko

研究成果: Article査読

1 被引用数 (Scopus)

抄録

Diethylstilbestrol and its derivatives were tested to determine their inhibitory effects on the relaxation activity of DNA topoisomerase I using cell lysates from Chinese hamster V79 cells. Among the derivatives investigated, (±)-indenestrol B, (±)-IB, showed the strongest inhibitory effect.

本文言語English
ページ(範囲)708-710
ページ数3
ジャーナルBiological and Pharmaceutical Bulletin
16
7
DOI
出版ステータスPublished - 1993 1 1

ASJC Scopus subject areas

  • 薬理学
  • 薬科学

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