Inhibitors of prostaglandin biosynthesis from dalbergia odorifera

Yukihiro Goda, Madoka Katayama, Kazuo Ichikawa, Masaaki Shibuya, Fumiyuki Kiuchi, Ushio Sankawa

研究成果: Article査読

33 被引用数 (Scopus)

抄録

From the heartwood of Dalbergia odorifera T. Chen, a Chinese medicinal drug (Japanese name “Koshinko”) used for the stagnation of disordered blood, five new phenolic compounds, isomucronustyrene (2) and hydroxyobtustyrene (3) (cinnamylphenol), (±)-isoduartin (6) (isoflavan), odoriflavene (7) (isoflav-3-ene) and (-)-odoricarpan (15) (pterocarpan) were isolated and their structures were elucidated on the basis of chemical and spectroscopic methods. Of the fifteen compounds isolated, the cinnamylphenols, isoflavans, isoflav-3-ene and a benzoic acid derivative inhibited prostaglandin biosynthesis more than the oterocarpan and isoflavone compounds.

本文言語English
ページ(範囲)5606-5609
ページ数4
ジャーナルChemical and Pharmaceutical Bulletin
33
12
DOI
出版ステータスPublished - 1985 1月 1
外部発表はい

ASJC Scopus subject areas

  • 化学 (全般)
  • 創薬

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