Inhibitors of Prostaglandin Biosynthesis from Dalbergia odorifera

Yukihiro Goda, Fumiyuki Kiuchi, Maaki Shibuya, Ushio Sankawa

研究成果: Article査読

64 被引用数 (Scopus)

抄録

The root heartwood of Dalbergia odorifera T. chen (Leguminosae) is a Chinese medicinal drug (Japanese name koshinko) used for a stagnant blood syndrome (stagnation of disordered blood; Japanese, oketsu). In addition to 10 known compounds, five new phenolic compounds, isomucronustyrene and hydroxyobtustyrene (cinnamylphenols), (4-)-isoduartin (isoflavan), odoriflavene (isoflav-3-ene) and (—)-odoricarpan (pterocarpan) were isolated and their structures were elucidated on the basis of chemical and spectroscopic methods. of the fifteen compounds isolated, cinnamylphenols, isoflavans, isoflavene and benzoic acid derivative significantly inhibited prostaglandin biosynthesis as well as platelet aggregation induced by arachidonic acid.

本文言語English
ページ(範囲)2452-2457
ページ数6
ジャーナルChemical and Pharmaceutical Bulletin
40
9
DOI
出版ステータスPublished - 1992 1月 1
外部発表はい

ASJC Scopus subject areas

  • 化学 (全般)
  • 創薬

フィンガープリント

「Inhibitors of Prostaglandin Biosynthesis from Dalbergia odorifera」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル