Inhibitory effect of brain natriuretic peptide on central angiotensin II-stimulated pressor response in conscious rats

Gotaro Shirakami, Kazuwa Nakao, Takayuki Yamada, Hiroshi Itoh, Kenjiro Mori, Kenji Kangawa, Naoto Minamino, Hisayuki Matsuo, Hiroo Imura

研究成果: Article査読

61 被引用数 (Scopus)

抄録

The effect of intracerebroventricular injection of brain natriuretic peptide (BNP) on blood pressure and heart rate was studied in conscious, unrestrained rats. The intracerebroventricular (i.c.v.) injection of BNP did not affect basal blood pressure and heart rate, but it attenuated i.c.v. angiotensin II (AII)-induced pressor response in a dose-dependent manner. These results suggest that BNP plays a role in the regulation of blood pressure in the central nervous system.

本文言語English
ページ(範囲)77-83
ページ数7
ジャーナルNeuroscience Letters
91
1
DOI
出版ステータスPublished - 1988 8月 15
外部発表はい

ASJC Scopus subject areas

  • 神経科学(全般)

フィンガープリント

「Inhibitory effect of brain natriuretic peptide on central angiotensin II-stimulated pressor response in conscious rats」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル