Inhibitory effect of the extracts from Thai medicinal plants on iNOS expression in mouse macrophage RAW 264.7

Tomonori Nakamura, Naoko Kodama, Takuya Kumamoto, Yoshihiro Higuchi, Chaiyo Chaichantipyuth, Koichi Ueno, Tsutomu Ishikawa, Shingo Yano

研究成果: Article査読

2 被引用数 (Scopus)

抄録

In the present study, we screened the inhibitory effect of the extract from 50 Thai medicinal plants on an inducible-nitric oxide synthase (iNOS) expression induced by lipopolysaccharide (LPS) in mouse macrophages RAW 264.7. From this screening, the extracts of root bark of Clausena guillauminii, C. lunulata, and C. excavata (Rutaceae) were found as the extracts which showed potent inhibitory effect on the iNOS protein expression in concentration- dependent manner. Furthermore, hydrophobic active components may exist in C. guillauminii.

本文言語English
ページ(範囲)107-110
ページ数4
ジャーナルJournal of Natural Medicines
63
1
DOI
出版ステータスPublished - 2009 1月
外部発表はい

ASJC Scopus subject areas

  • 薬科学
  • 創薬
  • 補完代替医療
  • 有機化学

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