TY - CHAP
T1 - Inositol trisphosphate receptors in the vascular development
AU - Uchida, Keiko
AU - Nakazawa, Maki
AU - Yamagishi, Chihiro
AU - Mikoshiba, Katsuhiko
AU - Yamagishi, Hiroyuki
N1 - Publisher Copyright:
© The Author(s) 2016.
Copyright:
Copyright 2016 Elsevier B.V., All rights reserved.
PY - 2016/1/1
Y1 - 2016/1/1
N2 - The placental circulation is crucial for the development of mammalian embryos [1]. The labyrinth layer in the placenta is created by extensive villous branching of the trophoblast and vascularization arising from the embryonic mesoderm. In the labyrinth, materials are exchanged between the maternal and embryonic circulation. Recently, we have found that inositol 1,4,5-trisphosphate (IP3) receptors (IP3Rs) may be required for the placental vascularization.
AB - The placental circulation is crucial for the development of mammalian embryos [1]. The labyrinth layer in the placenta is created by extensive villous branching of the trophoblast and vascularization arising from the embryonic mesoderm. In the labyrinth, materials are exchanged between the maternal and embryonic circulation. Recently, we have found that inositol 1,4,5-trisphosphate (IP3) receptors (IP3Rs) may be required for the placental vascularization.
KW - Angiogenesis
KW - Intracellular calcium
KW - Placenta
KW - Vascular development
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U2 - 10.1007/978-4-431-54628-3_32
DO - 10.1007/978-4-431-54628-3_32
M3 - Chapter
AN - SCOPUS:85006765716
SN - 9784431546276
SP - 237
EP - 239
BT - Etiology and Morphogenesis of Congenital Heart Disease
PB - Springer Japan
ER -