Interactions between transposable elements and Argonautes have (probably) been shaping the Drosophila genome throughout evolution

Haruhiko Siomi, Mikiko C. Siomi

研究成果: Review article査読

20 被引用数 (Scopus)

抄録

Transposable elements (TEs) are powerful mutagenic agents responsible for generating variation in the host genome. As TEs can be overtly deleterious, a variety of different mechanisms have evolved to keep their activities in check. In plants, fungi, and animals, RNA silencing has been implicated as a major defense against repetitive element transposition. This nucleic acid-based defense mechanism also appears to be directed at inherited silencing of TEs without altering the underlying DNA sequence. Complex interactions between TEs and RNA silencing machineries have been co-opted to regulate cellular genes.

本文言語English
ページ(範囲)181-187
ページ数7
ジャーナルCurrent Opinion in Genetics and Development
18
2
DOI
出版ステータスPublished - 2008 4
外部発表はい

ASJC Scopus subject areas

  • Genetics
  • Developmental Biology

フィンガープリント 「Interactions between transposable elements and Argonautes have (probably) been shaping the Drosophila genome throughout evolution」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル