Investigation of brain science and neurological/psychiatric disorders using genetically modified non-human primates

Hideyuki Okano, Noriyuki Kishi

研究成果: Review article査読

25 被引用数 (Scopus)

抄録

Although mice have been the most frequently used experimental animals in many research fields due to well-established gene manipulation techniques, recent evidence has revealed that rodent models do not always recapitulate pathophysiology of human neurological and psychiatric diseases due to the differences between humans and rodents. The recent developments in gene manipulation of non-human primate have been attracting much attention in the biomedical research field, because non-human primates have more applicable brain structure and function than rodents. In this review, we summarize recent progress on genetically-modified non-human primates including transgenic and knockout animals using genome editing technology.

本文言語English
ページ(範囲)1-6
ページ数6
ジャーナルCurrent Opinion in Neurobiology
50
DOI
出版ステータスPublished - 2018 6月

ASJC Scopus subject areas

  • 神経科学(全般)

フィンガープリント

「Investigation of brain science and neurological/psychiatric disorders using genetically modified non-human primates」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル