Investigation of the effect of discrete absorbers upon the measurement of blood volume with near-infrared spectroscopy

Michael Firbank, Eiji Okada, David T. Delpy

研究成果: Article査読

43 被引用数 (Scopus)

抄録

This paper derives an analytical model for investigating the effect of the distribution of absorbers upon light attenuation in a scattering medium. Results from this are found to agree with those of Monte Carlo simulations. The implications of this model are then examined for their likely effect upon the measurement of cerebral blood volume (CBV) using near-infrared (NIR) spectroscopy. We conclude that, given the small diameter of the majority of cerebral blood vessels, the distribution of the blood will have little effect upon the measurement of CBV. Where changes to the blood volume occur in the larger (>0.2 mm diameter) vessels on the surface of the brain, NIR spectroscopy is likely to underestimate the change.

本文言語English
ページ(範囲)465-477
ページ数13
ジャーナルPhysics in Medicine and Biology
42
3
DOI
出版ステータスPublished - 1997
外部発表はい

ASJC Scopus subject areas

  • 放射線技術および超音波技術
  • 放射線学、核医学およびイメージング

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