Ion-sensitive field effect transistor as a monovalent cation detector for ion chromatography and its application to the measurement of Na+ and K+ concentrations in serum

Kazuhiko Watanabe, Koji Tohda, Hitoshi Sugimoto, Fumihiko Eitoku, Hidenari Inoue, Koji Suzuki, Shigeru Nakamura

研究成果: Article査読

17 被引用数 (Scopus)

抄録

An ion-sensitive field effect transistor, which is a small potentiometric ion-sensing probe, was applied as a detector in the ion chromatography of alkali-metal cations. The cation-sensing transistor was prepared by coating the gate part of the probe to form a poly(vinyl chloride) matrix membrane containing tetranactin, which enables detection of alkali-metal ions such as Na+, K+, Rb+, and Cs+. To be able to analyse amounts less than 1 μl and make full use of the small ion-sensing probe, we constructed a miniature cation-exchange separation column (support 10 μm polystyrene) with a PTFE tube (20 mm × 1.5 mm I.D. × 2.1 mm O.D.). As an application of the system, Na+ and K+ concentrations in serum were determined. The analytical results for these two cations were good agreement with those obtained by flame photometry.

本文言語English
ページ(範囲)109-116
ページ数8
ジャーナルJournal of Chromatography B: Biomedical Sciences and Applications
566
1
DOI
出版ステータスPublished - 1991 5月 3

ASJC Scopus subject areas

  • 化学 (全般)

フィンガープリント

「Ion-sensitive field effect transistor as a monovalent cation detector for ion chromatography and its application to the measurement of Na+ and K+ concentrations in serum」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル