Iridium-Catalyzed Reductive Nucleophilic Addition to Secondary Amides

Yoshito Takahashi, Risa Yoshii, Takaaki Satou, Noritaka Chida

研究成果: Article

14 引用 (Scopus)

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An iridium-catalyzed reductive nucleophilic addition to secondary amides is reported. After the iridium-catalyzed reduction, the resulting imines can undergo the Strecker reaction, the Mannich reaction, allylation, and [3 + 2]-cycloaddition. The method shows high chemoselectivity in the presence of other functional groups such as methyl ester.

元の言語English
ページ(範囲)5705-5708
ページ数4
ジャーナルOrganic Letters
20
発行部数18
DOI
出版物ステータスPublished - 2018 9 21

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ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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