Is event-related desynchronization a biomarker representing corticospinal excitability?

Mitsuaki Takemi, Yoshihisa Masakado, Meigen Liu, Junichi Ushiba

研究成果: Conference contribution

9 引用 (Scopus)

抜粋

Brain computer interfaces (BCIs) using event-related desynchronization (ERD) of the electroencephalogram (EEG), which is believed to represent increased activation of the sensorimotor cortex, have attracted attention as tools for rehabilitation of upper limb motor functions in hemiplegic stroke patients. However, it remains unclear whether the corticospinal excitability is actually correlated with ERD. The purpose of this study was to assess the association between the ERD magnitude and the excitability of primary motor cortex (M1) and spinal motoneurons. M1 excitability was tested by motor evoked potentials (MEPs), short-interval intracortical inhibition (SICI) and intracortical facilitation (ICF) using transcranial magnetic stimulation, and spinal motoneuronal excitability was tested by F-waves using peripheral nerve stimulation. Results showed that large ERD during motor imagery was associated with significantly increased F-wave persistence and reduced SICI, but no significant changes in ICF and the response average of F-wave amplitudes. Our findings suggest that ERD magnitude during motor imagery represents the instantaneous excitability of both M1 and spinal motoneurons. This study provides electrophysiological evidence that ERD-based BCI with motor imagery task increases corticospinal excitability as changes accompanying actual movements.

元の言語English
ホスト出版物のタイトル2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
ページ281-284
ページ数4
DOI
出版物ステータスPublished - 2013 10 31
イベント2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013 - Osaka, Japan
継続期間: 2013 7 32013 7 7

出版物シリーズ

名前Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
ISSN(印刷物)1557-170X

Other

Other2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
Japan
Osaka
期間13/7/313/7/7

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

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  • これを引用

    Takemi, M., Masakado, Y., Liu, M., & Ushiba, J. (2013). Is event-related desynchronization a biomarker representing corticospinal excitability?2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013 (pp. 281-284). [6609492] (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). https://doi.org/10.1109/EMBC.2013.6609492