@article{d9febc3cd9d84f518f2ac5f1d9a77c67,
title = "Isolation and expression of a human SRY-related cDNA, hSOX20",
abstract = "SOX is a family of genes related to the testis-determining gene, SRY. We have isolated and sequenced an hSOX20 cDNA: from a cell line of human embryonic carcinoma. This cDNA contains an open reading frame (ORF) encoding 233 amino acids. The protein encompasses an SRY-type HMG box exhibiting strong homologies to those of mouse Sox15 and Sox16. Various adult and fetal tissues were tested for hSOX20 mRNA by Northern analysis. Its expression is restricted to the fetal testis and the size of the transcript is 1.5 knt. Electrophoretic mobility shift assay indicated that recombinant hSOX20 polypeptide is capable of binding to AACAAT sequence.",
keywords = "DNA binding, Embryonic carcinoma, Fetal testis, HMG box, SOX",
author = "Yoshiki Hiraoka and Motoyuki Ogawa and Yukinao Sakai and Koji Taniguchi and Takuma Fujii and Akihiro Umezawa and Hata, {Jun Ichi} and Sadakazu Aiso",
note = "Funding Information: This work was supported in part by a National Grant-in-Aid for the Establishment of High-Tech Research Center in a Private University from Minstry of Education, Science and Culture to S. A. and Grants-in Aids from Ministry of Education, Science and Culture to S. A. and Y. H., and by Keio Gakuji Fukuzawa Memorial Funds for the Advancement of Education and Research and Keio Gakuji Academic Developmental Funds from Keio University to S.A. and Y.H.",
year = "1998",
month = mar,
day = "9",
doi = "10.1016/S0167-4781(97)00186-3",
language = "English",
volume = "1396",
pages = "132--137",
journal = "Biochimica et Biophysica Acta - Gene Structure and Expression",
issn = "0167-4781",
publisher = "Elsevier BV",
number = "2",
}