Isolation of C11 cyclopentenones from two didemnid species, Lissoclinum sp. and Diplosoma sp.

Takayuki Ogi, Palupi Margiastuti, Toshiaki Teruya, Junsei Taira, Kiyotake Suenaga, Katsuhiro Ueda

研究成果: Article査読

21 被引用数 (Scopus)

抄録

A series of new C11 cyclopentenones 1-7 was isolated, together with four known metabolites 9/10, 12 and 13, from the extract of the didemnid ascidian Lissoclinum sp. The other didemnid ascidian Diplosoma sp. contained didemnenones 1, 2 and 5, and five known metabolites 8-12. The structures of 1-7 were elucidated by spectroscopic analyses. Cytotoxicity of the isolated compounds was evaluated against three human cancer cell lines (HCT116, A431 and A549).

本文言語English
ページ(範囲)816-832
ページ数17
ジャーナルMarine Drugs
7
4
DOI
出版ステータスPublished - 2009 12

ASJC Scopus subject areas

  • 創薬

フィンガープリント

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