Japanese nationwide surveillance in 2011 of antibacterial susceptibility patterns of clinical isolates from complicated urinary tract infection cases

Kiyohito Ishikawa, Ryoichi Hamasuna, Shinya Uehara, Mitsuru Yasuda, Shingo Yamamoto, Hiroshi Hayami, Satoshi Takahashi, Tetsuro Matsumoto, Shinichi Minamitani, Jun ichi Kadota, Satoshi Iwata, Mitsuo Kaku, Akira Watanabe, Keisuke Sunakawa, Junko Sato, Hideaki Hanaki, Taiji Tsukamoto, Hiroshi Kiyota, Shin Egawa, Takashi DeguchiMinori Matsumoto, Kazushi Tanaka, Soichi Arakawa, Masato Fujisawa, Hiromi Kumon, Kanao Kobayashi, Akio Matsubara, Hironobu Wakeda, Yoshinosuke Amemoto, Shoichi Onodera, Hirokazu Goto, Hisao Komeda, Masuo Yamashita, Tadasu Takenaka, Yoshinori Fujimoto, Masaya Tsugawa, Yoshito Takahashi, Hiroshi Maeda, Hiroyuki Onishi, Satoshi Ishitoya, Kazuo Nishimura, Kenji Mitsumori, Toru Ito, Yoshikazu Togo, Ichiro Nakamura, Noriyuki Ito, Sojun Kanamaru, Takaoki Hirose, Takashi Muranaka, Daisuke Yamada, Satoshi Ishihara, Hiroya Oka, Hisato Inatomi, Takashi Matsui, Makoto Kobuke, Yasuharu Kunishima, Takahiro Kimura, Takaharu Ichikawa, Ichiro Kagara, Masanori Matsukawa, Koichi Takahashi, Koji Mita, Masao Kato, Kazuhiro Okumura, Hiroaki Kawanishi, Takayuki Hashimura, Teruyoshi Aoyama, Masanobu Shigeta, Shuntaro Koda, Keisuke Taguchi, Yohei Matsuda

研究成果: Article

24 引用 (Scopus)

抄録

To investigate antimicrobial susceptibility patterns of various bacterial pathogens isolated from complicated urinary tract infection (UTI) cases, the Japanese Society of Chemotherapy, the Japanese Association of Infectious Disease, and the Japanese Society of Clinical Microbiology conducted the second nationwide surveillance from January to September 2011. With the cooperation of 42 medical institutions throughout Japan, 1036 strains belonging to 8 clinically relevant bacterial species were collected.Among methicillin-resistant Staphylococcus aureus (MRSA) strain, the vancomycin (VCM) MIC for 5.5% (3/55) of the strains was 2 μg/mL. Ampicillin, VCM, and linezolid were relatively active against 209 Enterococcus faecalis strains. The proportion of fluoroquinolone (FQ)-resistant strains was >20%.The MIC90 of FQs against the 382 Escherichia coli strains was 2-64 mg/L and the proportion resistant to FQs was approximately 30%. However, susceptibility of E. coli to sitafloxacin was still high (MIC90 = 2 mg/L). Fifty-eight (15.2%) of 382 E. coli, 6 (4.5%) of 132 Klebsiella pneumoniae, 1 (2.4%) of 41 Klebsiella oxytoca and 4 (6.8%) of 59 Proteus mirabilis strains were suspected of producing extended-spectrum beta-lactamase.Of 93 Pseudomonas aeruginosa strains, the proportions resistant to imipenem, amikacin, and ciprofloxacin were 21.5%, 4.3%, and 20.4%, respectively. Four strains (4.3%) were found to be multidrug-resistant.In complicated UTI cases, all of MRSA and E. faecalis were susceptible to all anti-MRSA agents. Sitafloxacin was active against other FQ-resistant E. coli strains. The isolation of extended-spectrum beta-lactamase-producing and multidrug-resistant strains increased.

元の言語English
ページ(範囲)623-633
ページ数11
ジャーナルJournal of Infection and Chemotherapy
21
発行部数9
DOI
出版物ステータスPublished - 2015 9 1
外部発表Yes

Fingerprint

Urinary Tract Infections
Methicillin-Resistant Staphylococcus aureus
Escherichia coli
Linezolid
Enterococcus faecalis
Fluoroquinolones
Vancomycin
beta-Lactamases
Klebsiella oxytoca
Proteus mirabilis
Amikacin
Imipenem
Klebsiella pneumoniae
Ampicillin
Ciprofloxacin
Microbiology
Pseudomonas aeruginosa
Communicable Diseases
Japan
Drug Therapy

ASJC Scopus subject areas

  • Microbiology (medical)
  • Pharmacology (medical)
  • Infectious Diseases

これを引用

Japanese nationwide surveillance in 2011 of antibacterial susceptibility patterns of clinical isolates from complicated urinary tract infection cases. / Ishikawa, Kiyohito; Hamasuna, Ryoichi; Uehara, Shinya; Yasuda, Mitsuru; Yamamoto, Shingo; Hayami, Hiroshi; Takahashi, Satoshi; Matsumoto, Tetsuro; Minamitani, Shinichi; Kadota, Jun ichi; Iwata, Satoshi; Kaku, Mitsuo; Watanabe, Akira; Sunakawa, Keisuke; Sato, Junko; Hanaki, Hideaki; Tsukamoto, Taiji; Kiyota, Hiroshi; Egawa, Shin; Deguchi, Takashi; Matsumoto, Minori; Tanaka, Kazushi; Arakawa, Soichi; Fujisawa, Masato; Kumon, Hiromi; Kobayashi, Kanao; Matsubara, Akio; Wakeda, Hironobu; Amemoto, Yoshinosuke; Onodera, Shoichi; Goto, Hirokazu; Komeda, Hisao; Yamashita, Masuo; Takenaka, Tadasu; Fujimoto, Yoshinori; Tsugawa, Masaya; Takahashi, Yoshito; Maeda, Hiroshi; Onishi, Hiroyuki; Ishitoya, Satoshi; Nishimura, Kazuo; Mitsumori, Kenji; Ito, Toru; Togo, Yoshikazu; Nakamura, Ichiro; Ito, Noriyuki; Kanamaru, Sojun; Hirose, Takaoki; Muranaka, Takashi; Yamada, Daisuke; Ishihara, Satoshi; Oka, Hiroya; Inatomi, Hisato; Matsui, Takashi; Kobuke, Makoto; Kunishima, Yasuharu; Kimura, Takahiro; Ichikawa, Takaharu; Kagara, Ichiro; Matsukawa, Masanori; Takahashi, Koichi; Mita, Koji; Kato, Masao; Okumura, Kazuhiro; Kawanishi, Hiroaki; Hashimura, Takayuki; Aoyama, Teruyoshi; Shigeta, Masanobu; Koda, Shuntaro; Taguchi, Keisuke; Matsuda, Yohei.

:: Journal of Infection and Chemotherapy, 巻 21, 番号 9, 01.09.2015, p. 623-633.

研究成果: Article

Ishikawa, K, Hamasuna, R, Uehara, S, Yasuda, M, Yamamoto, S, Hayami, H, Takahashi, S, Matsumoto, T, Minamitani, S, Kadota, JI, Iwata, S, Kaku, M, Watanabe, A, Sunakawa, K, Sato, J, Hanaki, H, Tsukamoto, T, Kiyota, H, Egawa, S, Deguchi, T, Matsumoto, M, Tanaka, K, Arakawa, S, Fujisawa, M, Kumon, H, Kobayashi, K, Matsubara, A, Wakeda, H, Amemoto, Y, Onodera, S, Goto, H, Komeda, H, Yamashita, M, Takenaka, T, Fujimoto, Y, Tsugawa, M, Takahashi, Y, Maeda, H, Onishi, H, Ishitoya, S, Nishimura, K, Mitsumori, K, Ito, T, Togo, Y, Nakamura, I, Ito, N, Kanamaru, S, Hirose, T, Muranaka, T, Yamada, D, Ishihara, S, Oka, H, Inatomi, H, Matsui, T, Kobuke, M, Kunishima, Y, Kimura, T, Ichikawa, T, Kagara, I, Matsukawa, M, Takahashi, K, Mita, K, Kato, M, Okumura, K, Kawanishi, H, Hashimura, T, Aoyama, T, Shigeta, M, Koda, S, Taguchi, K & Matsuda, Y 2015, 'Japanese nationwide surveillance in 2011 of antibacterial susceptibility patterns of clinical isolates from complicated urinary tract infection cases', Journal of Infection and Chemotherapy, 巻. 21, 番号 9, pp. 623-633. https://doi.org/10.1016/j.jiac.2015.05.014
Ishikawa, Kiyohito ; Hamasuna, Ryoichi ; Uehara, Shinya ; Yasuda, Mitsuru ; Yamamoto, Shingo ; Hayami, Hiroshi ; Takahashi, Satoshi ; Matsumoto, Tetsuro ; Minamitani, Shinichi ; Kadota, Jun ichi ; Iwata, Satoshi ; Kaku, Mitsuo ; Watanabe, Akira ; Sunakawa, Keisuke ; Sato, Junko ; Hanaki, Hideaki ; Tsukamoto, Taiji ; Kiyota, Hiroshi ; Egawa, Shin ; Deguchi, Takashi ; Matsumoto, Minori ; Tanaka, Kazushi ; Arakawa, Soichi ; Fujisawa, Masato ; Kumon, Hiromi ; Kobayashi, Kanao ; Matsubara, Akio ; Wakeda, Hironobu ; Amemoto, Yoshinosuke ; Onodera, Shoichi ; Goto, Hirokazu ; Komeda, Hisao ; Yamashita, Masuo ; Takenaka, Tadasu ; Fujimoto, Yoshinori ; Tsugawa, Masaya ; Takahashi, Yoshito ; Maeda, Hiroshi ; Onishi, Hiroyuki ; Ishitoya, Satoshi ; Nishimura, Kazuo ; Mitsumori, Kenji ; Ito, Toru ; Togo, Yoshikazu ; Nakamura, Ichiro ; Ito, Noriyuki ; Kanamaru, Sojun ; Hirose, Takaoki ; Muranaka, Takashi ; Yamada, Daisuke ; Ishihara, Satoshi ; Oka, Hiroya ; Inatomi, Hisato ; Matsui, Takashi ; Kobuke, Makoto ; Kunishima, Yasuharu ; Kimura, Takahiro ; Ichikawa, Takaharu ; Kagara, Ichiro ; Matsukawa, Masanori ; Takahashi, Koichi ; Mita, Koji ; Kato, Masao ; Okumura, Kazuhiro ; Kawanishi, Hiroaki ; Hashimura, Takayuki ; Aoyama, Teruyoshi ; Shigeta, Masanobu ; Koda, Shuntaro ; Taguchi, Keisuke ; Matsuda, Yohei. / Japanese nationwide surveillance in 2011 of antibacterial susceptibility patterns of clinical isolates from complicated urinary tract infection cases. :: Journal of Infection and Chemotherapy. 2015 ; 巻 21, 番号 9. pp. 623-633.
@article{4c6b377d9ded4b25b8ac6c2ce6d520ea,
title = "Japanese nationwide surveillance in 2011 of antibacterial susceptibility patterns of clinical isolates from complicated urinary tract infection cases",
abstract = "To investigate antimicrobial susceptibility patterns of various bacterial pathogens isolated from complicated urinary tract infection (UTI) cases, the Japanese Society of Chemotherapy, the Japanese Association of Infectious Disease, and the Japanese Society of Clinical Microbiology conducted the second nationwide surveillance from January to September 2011. With the cooperation of 42 medical institutions throughout Japan, 1036 strains belonging to 8 clinically relevant bacterial species were collected.Among methicillin-resistant Staphylococcus aureus (MRSA) strain, the vancomycin (VCM) MIC for 5.5{\%} (3/55) of the strains was 2 μg/mL. Ampicillin, VCM, and linezolid were relatively active against 209 Enterococcus faecalis strains. The proportion of fluoroquinolone (FQ)-resistant strains was >20{\%}.The MIC90 of FQs against the 382 Escherichia coli strains was 2-64 mg/L and the proportion resistant to FQs was approximately 30{\%}. However, susceptibility of E. coli to sitafloxacin was still high (MIC90 = 2 mg/L). Fifty-eight (15.2{\%}) of 382 E. coli, 6 (4.5{\%}) of 132 Klebsiella pneumoniae, 1 (2.4{\%}) of 41 Klebsiella oxytoca and 4 (6.8{\%}) of 59 Proteus mirabilis strains were suspected of producing extended-spectrum beta-lactamase.Of 93 Pseudomonas aeruginosa strains, the proportions resistant to imipenem, amikacin, and ciprofloxacin were 21.5{\%}, 4.3{\%}, and 20.4{\%}, respectively. Four strains (4.3{\%}) were found to be multidrug-resistant.In complicated UTI cases, all of MRSA and E. faecalis were susceptible to all anti-MRSA agents. Sitafloxacin was active against other FQ-resistant E. coli strains. The isolation of extended-spectrum beta-lactamase-producing and multidrug-resistant strains increased.",
keywords = "Complicated urinary tract infection, Surveillance, Susceptibility",
author = "Kiyohito Ishikawa and Ryoichi Hamasuna and Shinya Uehara and Mitsuru Yasuda and Shingo Yamamoto and Hiroshi Hayami and Satoshi Takahashi and Tetsuro Matsumoto and Shinichi Minamitani and Kadota, {Jun ichi} and Satoshi Iwata and Mitsuo Kaku and Akira Watanabe and Keisuke Sunakawa and Junko Sato and Hideaki Hanaki and Taiji Tsukamoto and Hiroshi Kiyota and Shin Egawa and Takashi Deguchi and Minori Matsumoto and Kazushi Tanaka and Soichi Arakawa and Masato Fujisawa and Hiromi Kumon and Kanao Kobayashi and Akio Matsubara and Hironobu Wakeda and Yoshinosuke Amemoto and Shoichi Onodera and Hirokazu Goto and Hisao Komeda and Masuo Yamashita and Tadasu Takenaka and Yoshinori Fujimoto and Masaya Tsugawa and Yoshito Takahashi and Hiroshi Maeda and Hiroyuki Onishi and Satoshi Ishitoya and Kazuo Nishimura and Kenji Mitsumori and Toru Ito and Yoshikazu Togo and Ichiro Nakamura and Noriyuki Ito and Sojun Kanamaru and Takaoki Hirose and Takashi Muranaka and Daisuke Yamada and Satoshi Ishihara and Hiroya Oka and Hisato Inatomi and Takashi Matsui and Makoto Kobuke and Yasuharu Kunishima and Takahiro Kimura and Takaharu Ichikawa and Ichiro Kagara and Masanori Matsukawa and Koichi Takahashi and Koji Mita and Masao Kato and Kazuhiro Okumura and Hiroaki Kawanishi and Takayuki Hashimura and Teruyoshi Aoyama and Masanobu Shigeta and Shuntaro Koda and Keisuke Taguchi and Yohei Matsuda",
year = "2015",
month = "9",
day = "1",
doi = "10.1016/j.jiac.2015.05.014",
language = "English",
volume = "21",
pages = "623--633",
journal = "Journal of Infection and Chemotherapy",
issn = "1341-321X",
publisher = "Elsevier BV",
number = "9",

}

TY - JOUR

T1 - Japanese nationwide surveillance in 2011 of antibacterial susceptibility patterns of clinical isolates from complicated urinary tract infection cases

AU - Ishikawa, Kiyohito

AU - Hamasuna, Ryoichi

AU - Uehara, Shinya

AU - Yasuda, Mitsuru

AU - Yamamoto, Shingo

AU - Hayami, Hiroshi

AU - Takahashi, Satoshi

AU - Matsumoto, Tetsuro

AU - Minamitani, Shinichi

AU - Kadota, Jun ichi

AU - Iwata, Satoshi

AU - Kaku, Mitsuo

AU - Watanabe, Akira

AU - Sunakawa, Keisuke

AU - Sato, Junko

AU - Hanaki, Hideaki

AU - Tsukamoto, Taiji

AU - Kiyota, Hiroshi

AU - Egawa, Shin

AU - Deguchi, Takashi

AU - Matsumoto, Minori

AU - Tanaka, Kazushi

AU - Arakawa, Soichi

AU - Fujisawa, Masato

AU - Kumon, Hiromi

AU - Kobayashi, Kanao

AU - Matsubara, Akio

AU - Wakeda, Hironobu

AU - Amemoto, Yoshinosuke

AU - Onodera, Shoichi

AU - Goto, Hirokazu

AU - Komeda, Hisao

AU - Yamashita, Masuo

AU - Takenaka, Tadasu

AU - Fujimoto, Yoshinori

AU - Tsugawa, Masaya

AU - Takahashi, Yoshito

AU - Maeda, Hiroshi

AU - Onishi, Hiroyuki

AU - Ishitoya, Satoshi

AU - Nishimura, Kazuo

AU - Mitsumori, Kenji

AU - Ito, Toru

AU - Togo, Yoshikazu

AU - Nakamura, Ichiro

AU - Ito, Noriyuki

AU - Kanamaru, Sojun

AU - Hirose, Takaoki

AU - Muranaka, Takashi

AU - Yamada, Daisuke

AU - Ishihara, Satoshi

AU - Oka, Hiroya

AU - Inatomi, Hisato

AU - Matsui, Takashi

AU - Kobuke, Makoto

AU - Kunishima, Yasuharu

AU - Kimura, Takahiro

AU - Ichikawa, Takaharu

AU - Kagara, Ichiro

AU - Matsukawa, Masanori

AU - Takahashi, Koichi

AU - Mita, Koji

AU - Kato, Masao

AU - Okumura, Kazuhiro

AU - Kawanishi, Hiroaki

AU - Hashimura, Takayuki

AU - Aoyama, Teruyoshi

AU - Shigeta, Masanobu

AU - Koda, Shuntaro

AU - Taguchi, Keisuke

AU - Matsuda, Yohei

PY - 2015/9/1

Y1 - 2015/9/1

N2 - To investigate antimicrobial susceptibility patterns of various bacterial pathogens isolated from complicated urinary tract infection (UTI) cases, the Japanese Society of Chemotherapy, the Japanese Association of Infectious Disease, and the Japanese Society of Clinical Microbiology conducted the second nationwide surveillance from January to September 2011. With the cooperation of 42 medical institutions throughout Japan, 1036 strains belonging to 8 clinically relevant bacterial species were collected.Among methicillin-resistant Staphylococcus aureus (MRSA) strain, the vancomycin (VCM) MIC for 5.5% (3/55) of the strains was 2 μg/mL. Ampicillin, VCM, and linezolid were relatively active against 209 Enterococcus faecalis strains. The proportion of fluoroquinolone (FQ)-resistant strains was >20%.The MIC90 of FQs against the 382 Escherichia coli strains was 2-64 mg/L and the proportion resistant to FQs was approximately 30%. However, susceptibility of E. coli to sitafloxacin was still high (MIC90 = 2 mg/L). Fifty-eight (15.2%) of 382 E. coli, 6 (4.5%) of 132 Klebsiella pneumoniae, 1 (2.4%) of 41 Klebsiella oxytoca and 4 (6.8%) of 59 Proteus mirabilis strains were suspected of producing extended-spectrum beta-lactamase.Of 93 Pseudomonas aeruginosa strains, the proportions resistant to imipenem, amikacin, and ciprofloxacin were 21.5%, 4.3%, and 20.4%, respectively. Four strains (4.3%) were found to be multidrug-resistant.In complicated UTI cases, all of MRSA and E. faecalis were susceptible to all anti-MRSA agents. Sitafloxacin was active against other FQ-resistant E. coli strains. The isolation of extended-spectrum beta-lactamase-producing and multidrug-resistant strains increased.

AB - To investigate antimicrobial susceptibility patterns of various bacterial pathogens isolated from complicated urinary tract infection (UTI) cases, the Japanese Society of Chemotherapy, the Japanese Association of Infectious Disease, and the Japanese Society of Clinical Microbiology conducted the second nationwide surveillance from January to September 2011. With the cooperation of 42 medical institutions throughout Japan, 1036 strains belonging to 8 clinically relevant bacterial species were collected.Among methicillin-resistant Staphylococcus aureus (MRSA) strain, the vancomycin (VCM) MIC for 5.5% (3/55) of the strains was 2 μg/mL. Ampicillin, VCM, and linezolid were relatively active against 209 Enterococcus faecalis strains. The proportion of fluoroquinolone (FQ)-resistant strains was >20%.The MIC90 of FQs against the 382 Escherichia coli strains was 2-64 mg/L and the proportion resistant to FQs was approximately 30%. However, susceptibility of E. coli to sitafloxacin was still high (MIC90 = 2 mg/L). Fifty-eight (15.2%) of 382 E. coli, 6 (4.5%) of 132 Klebsiella pneumoniae, 1 (2.4%) of 41 Klebsiella oxytoca and 4 (6.8%) of 59 Proteus mirabilis strains were suspected of producing extended-spectrum beta-lactamase.Of 93 Pseudomonas aeruginosa strains, the proportions resistant to imipenem, amikacin, and ciprofloxacin were 21.5%, 4.3%, and 20.4%, respectively. Four strains (4.3%) were found to be multidrug-resistant.In complicated UTI cases, all of MRSA and E. faecalis were susceptible to all anti-MRSA agents. Sitafloxacin was active against other FQ-resistant E. coli strains. The isolation of extended-spectrum beta-lactamase-producing and multidrug-resistant strains increased.

KW - Complicated urinary tract infection

KW - Surveillance

KW - Susceptibility

UR - http://www.scopus.com/inward/record.url?scp=84939573549&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84939573549&partnerID=8YFLogxK

U2 - 10.1016/j.jiac.2015.05.014

DO - 10.1016/j.jiac.2015.05.014

M3 - Article

C2 - 26166322

AN - SCOPUS:84939573549

VL - 21

SP - 623

EP - 633

JO - Journal of Infection and Chemotherapy

JF - Journal of Infection and Chemotherapy

SN - 1341-321X

IS - 9

ER -