Kinetics of dimension-restricted conditions

Noriko Hiroi, Akira Funahashi

研究成果: Chapter

2 被引用数 (Scopus)


The intracellular environment is crowded with skeletal proteins, organelle membranes, ribosomes, and so on. When molecular movement is restricted by such environments, some biochemical reaction processes cannot be represented by classical models, which assume that reactions occur in simple Newtonian fluids. Dimension-restricted reaction kinetics (DRRK) modeling is a method that can represent dimension-restricted reactions. We introduce the methods of DRRK in each case of reaction type. DRRK has another advantage in that it can be quantitatively evaluated by biochemical experiments. We also introduce the procedure of applying it for experimental results. This modeling method may provide the basis for in vivo-oriented modeling.

ホスト出版物のタイトルIntroduction to Systems Biology
出版社Humana Press
出版ステータスPublished - 2007 12 1

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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