Knot-Tying Force During Suturing and Wound Healing in the Gastrointestinal Tract

Junya Oguma, Soji Ozawa, Yasuhide Morikawa, Toshiharu Furukawa, Yuko Kitagawa, Masakazu Ueda, Masaki Kitajima

研究成果: Article査読

8 被引用数 (Scopus)

抄録

Background: Objective data should be obtained to determine the most suitable knot-tying force for appropriate suturing during robotic surgery. The purpose of this study was to estimate the appropriate force by investigating the efficiency of wound healing in the gastrointestinal tract in dog models. Methods: We cut and sutured the stomach and jejunum of 12 beagles, using different magnitudes of knot-tying forces. The relationship between the knot-tying force and variations in the density of the microvessels and basic-fibroblast growth factor (bFGF)-positive cells were evaluated. Results: On the 7th postoperative day (POD) in the stomach, and the 7th and 11th POD in the jejunum, the density of the microvessels in the submucosa at the sites of cutting and ligation was higher for the knot-tying force of 1.5 N than for any other forces used. On the 4th and 7th POD in the stomach and 11th POD in the jejunum, the density of bFGF-positive cell in the mucosa was higher for the knot-tying force of 1.5 N than for any of the other forces used. Conclusions: By assessing the efficiency of wound healing, it was determined that the knot-tying force of 1.5 N may be the most appropriate for optimal wound healing in the gastrointestinal tract of the beagles.

本文言語English
ページ(範囲)129-134
ページ数6
ジャーナルJournal of Surgical Research
140
1
DOI
出版ステータスPublished - 2007 6 1

ASJC Scopus subject areas

  • Surgery

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