Laser-driven short-duration heating angioplasty: Dilatation performance in cadaver atherosclerotic femoral arteries

Natsumi Shimazaki, Sho Naruse, Tsunenori Arai, Nobuaki Imanishi, Sadakazu Aiso

研究成果: Conference contribution

抜粋

The purpose of this study was to investigate the artery dilatation performance of the short-duration heating balloon catheter in cadaver stenotic arteries. We designed a prototype short-duration heating balloon catheter that can heat artery media to around 60 °C in 15-25 s by a combination of laser-driven heat generation and continuous fluid irrigation in the balloon. We performed ex vivo short-duration heating dilatation in the cadaver atherosclerotic femoral arteries (initial percent diameter stenosis was 36-98%), with the maximum balloon temperature of 65±5 °C, laser irradiation duration of 25 s, and balloon dilatation pressure of 3.5 atm. The artery lumen configurations before and after the dilatations were assessed with a commercial IVUS system. After the short-duration heating dilatations, the percent diameter stenosis was reduced below 30% without any artery tears or dissections. We estimated that the artery media temperature was raised to around 60 °C in which plaque thickness was below 0.8 mm by a thermal conduction calculation. The estimated maximum temperature in artery adventitia and surrounding tissue was up to 45 °C. We found that the short-duration heating balloon could sufficiently dilate the cadaver stenotic arteries, without thermal injury in artery adventitia and surroundings.

元の言語English
ホスト出版物のタイトルPhotonic Therapeutics and Diagnostics IX
DOI
出版物ステータスPublished - 2013 5 30
イベントPhotonic Therapeutics and Diagnostics IX - San Francisco, CA, United States
継続期間: 2013 2 22013 2 7

出版物シリーズ

名前Progress in Biomedical Optics and Imaging - Proceedings of SPIE
8565
ISSN(印刷物)1605-7422

Other

OtherPhotonic Therapeutics and Diagnostics IX
United States
San Francisco, CA
期間13/2/213/2/7

    フィンガープリント

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

これを引用

Shimazaki, N., Naruse, S., Arai, T., Imanishi, N., & Aiso, S. (2013). Laser-driven short-duration heating angioplasty: Dilatation performance in cadaver atherosclerotic femoral arteries. : Photonic Therapeutics and Diagnostics IX [85654E] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; 巻数 8565). https://doi.org/10.1117/12.2005432