Lead induced increase of blood pressure in female lead workers

K. Nomiyama, H. Nomiyama, S. J. Liu, Y. X. Tao, T. Nomiyama, K. Omae

研究成果: Article

17 引用 (Scopus)


Aims: Although lead exposure has, in the absence of mathematical modelling, been believed to elevate blood pressure in females, it is necessary to clarify the relation between lead and blood pressure by eliminating confounding factors in the analysis. Methods: Blood lead was measured in 193 female workers, including 123 lead exposed workers. Possible confounding factors were controlled by multiple regression analyses. Results and Conclusion: Blood lead above 40 μg/dl was found to be the most potent factor for elevating systolic/diastolic blood pressure. Aging, urine protein, and plasma triglyceride also contributed to systolic/diastolic/pulse pressure increase, but hypertensive heredity did not. Data suggested that lead induced changes in lipoprotein metabolism may play an important role in the lead induced blood pressure increase in female workers.

ジャーナルOccupational and Environmental Medicine
出版物ステータスPublished - 2002 11 1


ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health


Nomiyama, K., Nomiyama, H., Liu, S. J., Tao, Y. X., Nomiyama, T., & Omae, K. (2002). Lead induced increase of blood pressure in female lead workers. Occupational and Environmental Medicine, 59(11), 734-738. https://doi.org/10.1136/oem.59.11.734