[Limbic encephalitis up to date].

Morinobu Seki, Shigeaki Suzuki, Norihiro Suzuki

研究成果: Article査読

3 被引用数 (Scopus)

抄録

Limbic encephalitis (LE) refers to an inflammatory disorder involving the hippocampus, amygdala and insular cortex. LE is now regarded as a more frequent disorder than it was previously thought, and the concept of LE has been expanded because of the development of neuroimaging and the increasing recognition of the associated antibodies. We categorized LE into 5 groups. LE caused by virus infection, autoantibody-mediated LE, LE with autoimmune disease, LE associated with drugs and LE during pregnancy. LE having the antibodies against intracellular antigens frequently related to cancer and are resistant to treatment. While, LE with antibodies against cell-membrane antigens, including NMDAR, AMPAR, GABA(B)R, VGKC, tend to respond better to antitumor therapy and immunotherapy.

本文言語English
ページ(範囲)442-447
ページ数6
ジャーナルNippon rinsho. Japanese journal of clinical medicine
69
3
出版ステータスPublished - 2011 3 1

ASJC Scopus subject areas

  • 医学(全般)

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