Liquid chromatography-mass spectrometry for the determination of medetomidine and other anaesthetics in plasma

Hideko Kanazawa, Yoshiko Nagata, Yoshikazu Matsushima, Nobuharu Takai, Hidefumi Uchiyama, Ryohei Nishimura, Akira Takeuchi

研究成果: Article査読

26 被引用数 (Scopus)

抄録

A liquid chromatographic-atmospheric pressure chemical ionization mass spectrometric method is presented for the simultaneous determination of medetomidine and other anaesthetic drugs in solutions and dog plasma. The drugs examined were flumazenil, butorphanol, atropine, ketamine, xylazine, medetomidine, atipamezole and midazolam. The separation was carried out on a reversed-phase column using methanol-0.1 M ammonium acetate (3:2) as eluent.

本文言語English
ページ(範囲)215-220
ページ数6
ジャーナルJournal of Chromatography A
631
1-2
DOI
出版ステータスPublished - 1993 2月 12

ASJC Scopus subject areas

  • 分析化学
  • 生化学
  • 有機化学

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