Lithiation of 1,2-dichloroethene in flow microreactors: Versatile synthesis of alkenes and alkynes by precise residence-time control

Aiichiro Nagaki; Chika Matsuo; Songhee Kim; Kodai Saito; Atsuo Miyazaki; Jun Ichi Yoshida

doi:10.1002/anie.201108932

Lithiation of 1,2-dichloroethene in flow microreactors: Versatile synthesis of alkenes and alkynes by precise residence-time control

Aiichiro Nagaki, Chika Matsuo, Songhee Kim, Kodai Saito, Atsuo Miyazaki, Jun Ichi Yoshida

研究成果: Article › 査読

85 被引用数 (Scopus)

抄録

It′s all about the timing: Precise control of the residence time (t ^Rx; see picture) of reactive intermediates in flow microreactors enables the reaction pathway of lithiated 1,2-dichloroethene to be switched to produce either alkenes or alkynes. This method also allows versatile syntheses of asymmetric disubstituted dichloroalkenes and alkynes.

本文言語	English
ページ（範囲）	3245-3248
ページ数	4
ジャーナル	Angewandte Chemie - International Edition
巻	51
号	13
DOI	https://doi.org/10.1002/anie.201108932
出版ステータス	Published - 2012 3月 26
外部発表	はい

ASJC Scopus subject areas

触媒
化学 (全般)

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10.1002/anie.201108932

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引用スタイル

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