Long-Term in vivo Experiment Protocol Using SD Rats

T. Ito, Y. Koya, N. Miki

研究成果: Conference contribution

抄録

Our group has been developing implantable artificial dialysis system to decrease burden of chronic kidney disease patients. To evaluate the device, long-Term in vivo experiments are mandatory. However, we need to complete the detailed design of the devices prior to the long-Term tests, which range from the temporal change of the device performance to time to surgical procedures. To do so, we need to conduct mid-and long-Term in vivo experiments for multiple times to acquire sufficient information. It is useful to use small animals, such as rats, for in vivo experiment. However, there is no prior work that discusses mid-and long-Term coagulation ability control in small animals. In this study, we investigated the heparin administration to manage the coagulability. A simplified device was connected to SD rats under coagulability control and the blood coagulation in the device was characterized. And succeeded in blood clotting inhibition for 48 hours

本文言語English
ホスト出版物のタイトル2019 International Conference on Electronics Packaging, ICEP 2019
出版社Institute of Electrical and Electronics Engineers Inc.
ページ144-148
ページ数5
ISBN(電子版)9784990218867
DOI
出版ステータスPublished - 2019 4
イベント2019 International Conference on Electronics Packaging, ICEP 2019 - Niigata, Japan
継続期間: 2019 4 172019 4 20

出版物シリーズ

名前2019 International Conference on Electronics Packaging, ICEP 2019

Conference

Conference2019 International Conference on Electronics Packaging, ICEP 2019
国/地域Japan
CityNiigata
Period19/4/1719/4/20

ASJC Scopus subject areas

  • 電子工学および電気工学
  • 電子材料、光学材料、および磁性材料
  • 金属および合金

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