Longitudinal magnetic resonance imaging study on whiplash injury patients: Minimum 10-year follow-up

Daisuke Ichihara, Eijiro Okada, Kazuhiro Chiba, Yoshiaki Toyama, Hirokazu Fujiwara, Suketaka Momoshima, Yuji Nishiwaki, Takeshi Hashimoto, Jun Ogawa, Masahiko Watanabe, Takeshi Takahata, Morio Matsumoto

研究成果: Article

18 引用 (Scopus)

抄録

Background: We conducted a prospective long-term follow-up study to assess associations between magnetic resonance imaging (MRI) findings and changes in clinical symptoms, as well as factors relating to the prognosis of symptoms. Methods: A total of 133 patients with acute whiplash injury between 1993 and 1996 participated in this follow-up study. They underwent neurological examinations by spine surgeons and second MRI scans of the cervical spine were obtained. They also filled out a questionnaire regarding cervical symptoms and the accident details. The items evaluated by MRI were (1) a decrease in the signal intensity of the intervertebral disc; (2) anterior compression of the dura and the spinal cord; (3) posterior disc protrusion; (4) disc space narrowing; and (5) foraminal stenosis. Relations between the presence/absence of degenerative changes on MRI, accident details, and patients' symptoms were assessed by calculating the adjusted odds ratio (OR). Results: Progression of some degenerative changes was recognized on MRI in 98.5% of the 133 whiplash injury patients, and clinical symptoms diminished in more than a half of the 133 patients. There were no statistically significant associations between MRI findings and changes in clinical symptoms. The prognosis for neck pain tended to be poor after accidents with double collisions (rear-end collision followed by frontend collision) [adjusted OR 5.83, 95% confidence interval (CI) 1.15-29.71] and accidents with serious car damage (2.87, 1.03-7.99). The prognosis for stiff shoulders tended to be poor in women (2.83, 1.23-6.51); and the prognosis for numbness in the upper extremities tended to be poor after accidents with serious car damage (3.39, 1.14-10.06). Conclusions: This study demonstrated that progression of degenerative changes of the cervical spine on MRI was not associated with clinical symptoms during the 10-year period after whiplash injury.

元の言語English
ページ(範囲)602-610
ページ数9
ジャーナルJournal of Orthopaedic Science
14
発行部数5
DOI
出版物ステータスPublished - 2009 9

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Whiplash Injuries
Magnetic Resonance Imaging
Accidents
Spine
Odds Ratio
Spinal Cord Compression
Hypesthesia
Neck Pain
Intervertebral Disc
Neurologic Examination
Upper Extremity
Pathologic Constriction
Confidence Intervals

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine

これを引用

Longitudinal magnetic resonance imaging study on whiplash injury patients : Minimum 10-year follow-up. / Ichihara, Daisuke; Okada, Eijiro; Chiba, Kazuhiro; Toyama, Yoshiaki; Fujiwara, Hirokazu; Momoshima, Suketaka; Nishiwaki, Yuji; Hashimoto, Takeshi; Ogawa, Jun; Watanabe, Masahiko; Takahata, Takeshi; Matsumoto, Morio.

:: Journal of Orthopaedic Science, 巻 14, 番号 5, 09.2009, p. 602-610.

研究成果: Article

Ichihara, Daisuke ; Okada, Eijiro ; Chiba, Kazuhiro ; Toyama, Yoshiaki ; Fujiwara, Hirokazu ; Momoshima, Suketaka ; Nishiwaki, Yuji ; Hashimoto, Takeshi ; Ogawa, Jun ; Watanabe, Masahiko ; Takahata, Takeshi ; Matsumoto, Morio. / Longitudinal magnetic resonance imaging study on whiplash injury patients : Minimum 10-year follow-up. :: Journal of Orthopaedic Science. 2009 ; 巻 14, 番号 5. pp. 602-610.
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abstract = "Background: We conducted a prospective long-term follow-up study to assess associations between magnetic resonance imaging (MRI) findings and changes in clinical symptoms, as well as factors relating to the prognosis of symptoms. Methods: A total of 133 patients with acute whiplash injury between 1993 and 1996 participated in this follow-up study. They underwent neurological examinations by spine surgeons and second MRI scans of the cervical spine were obtained. They also filled out a questionnaire regarding cervical symptoms and the accident details. The items evaluated by MRI were (1) a decrease in the signal intensity of the intervertebral disc; (2) anterior compression of the dura and the spinal cord; (3) posterior disc protrusion; (4) disc space narrowing; and (5) foraminal stenosis. Relations between the presence/absence of degenerative changes on MRI, accident details, and patients' symptoms were assessed by calculating the adjusted odds ratio (OR). Results: Progression of some degenerative changes was recognized on MRI in 98.5{\%} of the 133 whiplash injury patients, and clinical symptoms diminished in more than a half of the 133 patients. There were no statistically significant associations between MRI findings and changes in clinical symptoms. The prognosis for neck pain tended to be poor after accidents with double collisions (rear-end collision followed by frontend collision) [adjusted OR 5.83, 95{\%} confidence interval (CI) 1.15-29.71] and accidents with serious car damage (2.87, 1.03-7.99). The prognosis for stiff shoulders tended to be poor in women (2.83, 1.23-6.51); and the prognosis for numbness in the upper extremities tended to be poor after accidents with serious car damage (3.39, 1.14-10.06). Conclusions: This study demonstrated that progression of degenerative changes of the cervical spine on MRI was not associated with clinical symptoms during the 10-year period after whiplash injury.",
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AU - Ichihara, Daisuke

AU - Okada, Eijiro

AU - Chiba, Kazuhiro

AU - Toyama, Yoshiaki

AU - Fujiwara, Hirokazu

AU - Momoshima, Suketaka

AU - Nishiwaki, Yuji

AU - Hashimoto, Takeshi

AU - Ogawa, Jun

AU - Watanabe, Masahiko

AU - Takahata, Takeshi

AU - Matsumoto, Morio

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