Lung adenocarcinoma with repetitive endotracheal/endobronchial metastasis 20 years after surgery: A case report

Yohei Maki, Yoshifumi Kimizuka, Hisashi Sasaki, Takayuki Yamamoto, Chie Watanabe, Tomoya Sano, Yoichi Tagami, Kazuhisa Misawa, Jun Miyata, Yuji Fujikura, Hideyuki Shimazaki, Akihiko Kawana

研究成果: Article査読

1 被引用数 (Scopus)

抄録

The occurrence of endotracheal/endobronchial metastasis (EEM) after complete resection of a primary lung cancer is rare. Here, we report the case of an 86-year-old woman in whom EEM occurred twice over a 20-year period following complete resection of a primary adenocarcinoma localized to the left main bronchus and trachea. The presence of EEM was confirmed by establishing immunohistochemical homology of the metastases with the primary tumor. To the best of our knowledge, this is the first reported case of repetitive EEM of primary lung adenocarcinoma. Lymphatic invasion in the primary lesion suggested that a possible route for EEM was the peripheral lymphatic tract, explaining the slow recurrence rate. We conclude that observation of the trachea/bronchus over a long period post operation could be important in monitoring for EEM, particularly if lymphatic invasion is confirmed in the primary tumor.

本文言語English
ページ(範囲)133-136
ページ数4
ジャーナルThoracic Cancer
12
1
DOI
出版ステータスPublished - 2021 1月
外部発表はい

ASJC Scopus subject areas

  • 腫瘍学
  • 呼吸器内科

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