Marked reduction in the minimum inhibitory concentration (MIC) of β- lactams in methicillin-resistant Staphylococcus aureus produced by epicatechin gallate, an ingredient of green tea (Camellia sinensis)

Sumiko Shiota, Masato Shimizu, Tohru Mizushima, Hideyuki Ito, Tsutomu Hatano, Takashi Yoshida, Tomofusa Tsuchiya

研究成果: Article査読

109 被引用数 (Scopus)

抄録

We found that epicatechin gallate, a constituent of an extract of tea leaves (green tea) markedly lowered the minimum inhibitory concentration (MIC) of oxacillin and other β-lactams, but not of other antibacterial agents tested, in strains of methicillin-resistant Staphylococcus aureus. The antibacterial action of epicatechin gallate plus oxacillin was a bactericidal one.

本文言語English
ページ(範囲)1388-1390
ページ数3
ジャーナルBiological and Pharmaceutical Bulletin
22
12
DOI
出版ステータスPublished - 1999 12月

ASJC Scopus subject areas

  • 薬理学
  • 薬科学

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