Measurement of cryoprotectant concentration using MRI in pseudobiological tissues and determination of diffsivity based on inverse problem analysis

Hiroshi Ishiguro, Takanori Kai, Kuniyasu Ogawa

研究成果: Conference contribution

抄録

Transient one-dimensional distribution of cryoprotectant concentration in pseudobiological tissues (agar) was measured noninvasively using magnetic resonance imaging (MRI). Cryoprotectants were dimethyl sulfoxide (DMSO) and glycerol, common cryoprotectants penetrating cells. Attenuation of MRI image intensity due to volumetric fraction of solution and relaxation times was also investigated. Apparent diffusivity of each cryoprotectant as a function of agar concentration was determined from the inverse problem analysis. The diffusivity decreased with an increase in agar concentration. This method was also applied to the liver tissues of chicken.

本文言語English
ホスト出版物のタイトルAdvances in Heat and Mass Transfer in Biotechnology
出版社American Society of Mechanical Engineers (ASME)
ページ23-27
ページ数5
ISBN(印刷版)0791836398, 9780791836392
出版ステータスPublished - 2002 1 1

出版物シリーズ

名前ASME International Mechanical Engineering Congress and Exposition, Proceedings

ASJC Scopus subject areas

  • 機械工学

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