Mechanical pumpless giant liposome trapping system using parylene micro filter for biological assay

Y. Abe, K. Kamiya, T. Osaki, R. Kawano, N. Miki, S. Takeuchi

研究成果: Conference contribution

2 被引用数 (Scopus)

抄録

This paper proposes a non-chemical, mechanical giant liposome trapping method using a parylene filter with micrometer-order-sized holes. Giant liposomes can be useful reaction sites for biological assays, where immobilization of the liposomes is the key protocol for microscopic observation. The proposed mechanical trapping method using the parylene filter and gentle flow does not require pretreatments on the liposomes that are time consuming and costly. In addition, this method does not strongly bind but only traps the liposomes, which allows the liposomes to be chemically treated while being trapped and then, to be released. We demonstrated size-dependent trapping, solution exchange and releasing of liposomes. The proposed trapping method and microfluidic device are readily applicable to highly efficient giant liposome assays.

本文言語English
ホスト出版物のタイトルIEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013
ページ949-950
ページ数2
DOI
出版ステータスPublished - 2013
イベントIEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013 - Taipei, Taiwan, Province of China
継続期間: 2013 1 202013 1 24

出版物シリーズ

名前Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
ISSN(印刷版)1084-6999

Other

OtherIEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013
CountryTaiwan, Province of China
CityTaipei
Period13/1/2013/1/24

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Mechanical Engineering
  • Electrical and Electronic Engineering

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